Simvastatin 79902-63-9 CAS 79902-63-9
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Product name: simvastatin
CAS#:79902-63-9
Molecular formula: C25H38O5
Appearance: white or almost white powder or crystalline powder.
Use: Simvastatin is a hypolipidemic drug used to control elevated cholesterol, or hypercholesterolemia. It is a member of the statin class of pharmaceuticals.
Function:
It has effects on relieving pressure and stabilization. It can lower blood pressure
and slow heart rate. It has tranquillizing effect on psychotic mania.
Specification
Items | Specification | Results |
Appearance | A white or almost white, crystalline powder | Complies |
Identification | IR/HPLC | Complies |
Specific optical rotation | +285°- +298° | +292.1° |
Heavy metals | ≤20ppm | <20ppm |
Loss on drying | ≤0.5% | 0.10% |
Sulphated ash | ≤0.1% | <0.1% |
Chromatographic purity | ||
Simvastatin hydroxyacid | ≤0.4% | 0.12% |
Lovastatin and epilovastatin | ≤1.0 % | 0.26% |
Methylene simvastatin | ≤0.4% | 0.10% |
Acetyl simvastatin | ≤0.4% | 0.04% |
Anhydro simvastatin | ≤0.4% | 0.04% |
Simvastatin dimer | ≤0.4% | 0.08% |
Any other individual impurity | ≤0.1% | 0.06% |
Totalimpurities(Except lovastatin and epilovastatin) | ≤1.0% | 0.46% |
Assay | 98.0%-101.0% | 99.20% |
Packing:
25 kg/barrels, 1 kg/aluminum foil
Storage:
Sealed save, cool ventilated dry place, prevent sun, rain.
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