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Voglibose Basen 83480-29-9
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Voglibose Basic information
Product Name: Voglibose
Synonyms: VOGLIBOSE;3,4-DIDEOXY-4-[[2-HYDROXY-1-(HYDROXYMETHYL)ETHYL]AMINO]-2-C-(HYDROXYMETHYL)-D-EPIINOSITOL;3,4-DIDEOXY-4-[[2-HYDROXY-1-(HYDROXYMETHYL)ETHYL]AMINO]-2-C-(HYDROXYMETHYL)-D-EPINOSITOL;5-(1,3-dihydroxypropan-2-ylamino)-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol;VOGLIBOSE, 99+%;A 71100;AO 128;Basen
CAS: 83480-29-9
MF: C10H21NO7
MW: 267.28
EINECS:
Product Categories: Miscellaneous;VOGLIBOSE;All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Carbohydrates & Derivatives;Diabetes Research
Mol File: 83480-29-9.mol
Voglibose Usage And Synthesis
Chemical Properties Colourless Crystalline Solid
Usage An alpha-Glucosidase inhibitor used as an antidiabetic
Usage An α-Glucosidase inhibitor used as an antidiabetic.
Usage For the treatment of diabetes. It is specifically used for lowering post-prandial blood glucose levels thereby reducing the risk of macrovascular complications.
Biological Activity Orally active α -glucosidase inhibitor (IC 50 values are 3.9 and 6.4 nM at sucrase and maltase respectively). Increases glucagon-like peptide 1 (GLP-1) secretion and decreases food consumption in ob/ob mice, and reduces plasma concentrations of glucose, triglycerides and insulin in Wistar fatty rats. Exhibits antidiabetic and antiobesity activity in vivo .
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