Specifications Polymyxin B Sulfate 99%, Poylyxin B Sulfate BP/USP/EP Polymyxin B Sulphate 1. CA…
Polymyxin B Sulphate
1. CAS: 1405-20-5
2. Quality: EP6/USP35
3. Appearance: White to alomost white powder, hygroscopic
5. Use:
Polymyxin B sulfate is a mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa
strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on
cell membranes. Polymyxin B is used for infections with gramnegative organisms, but may be neurotoxic
and nephrotoxic. All gram-positive bacteria, fungi, and the gram
egative cocci, N. gonorrhea and N. menigitidis, are resistant. It is appropriate for treatment of infections
of the urinary tract, meninges, and blood stream, caused by susceptible strains of Pseudomonas
aeruginosa
6. Our advantage:
(1) 26 year experience in pharmaceutical and botanical industry
(2) ISO9001: 2008 certificated company
(3) Fischer Chemicals AG China office
ITEMS | SPECIFICATION of Polymyxin B Sulphate |
DESCRIPTION | WHITE TO ALMOST WHITE POWDER,HYGROSCOPIC. |
SOLUBILITY | FREELY SOLUBLE IN WATER;SLIGHTLY SOLUBLE IN ALCOHOL. |
IDENTIFICATION | A. LIQUID CHROMATOGRAPHIC IDENTIFICATION TEST B. A REDDISH VIOLET COLOR IS PRODUCED C. TEST FOR SULFATE |
PH(2%) | 5.0~7.0 |
PH(0.5%) | 5.0~7.5 |
SPECIFIC ROTATION | -78°- -90° |
LOSS ON DRYING | NOT MORE THAN 7.0% |
PHENYLALANINE | 9.0%~12.0% |
SULPHATED ASH | NOT MORE THAN 0.75% |
SULPHATE | 15.5%~17.5% |
HEAVY METALS | NOT MORE THAN 20PPM |
ASSAY(MICROBIAL) (ON DRIED BASIS) | NOT LESS THAN 6500IU/MG |
PARTICLE SIZE | 99.0%:NOT MORE THAN 30um BY VOL. 90.0%:NOT MORE THAN 25um BY VOL. 75.0%:NOT MORE THAN 20um BY VOL. MEAN DIAMETER:NOT MORE THAN 8.0UM |