treating brain tumors belustine; ceenu cecenu
CCNU is the trade name for lomustine. CeeNU is another name for lomustine.
In some cases, health care professionals may use the trade name CCNU or other
names CeeNu when referring to the generic drug name lomustine.
Lomustine is an anti-cancer ("antineoplastic" or "cytotoxic") chemotherapy drug. This
medication is classified as an "alkylating agent."
The application of Lomustine
· Treatment of brain tumors, both primary (developed in the brain) and metastatic (spread from another source).
· Hodgkin's disease and non-Hodgkin's lymphoma.
· Also has been used in treatment of melanoma, lung and colon cancer
Formula |
C9H16CIN3O2 |
Molecular weight |
233.70 |
EINECS |
235-859-2 |
CAS RN |
13010-47-4 |
CAS Name |
|
Synonyms: |
1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea; (chloro-2-ethyl)-1-cyclohexyl-3-nitrosourea; (cloro-2-etil)-1-cicloesil-3-nitrosourea; 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosoure; 1-(2-chloroethyl)-3-cyclohexyl-1-nitroso-ure; belustine; cecenu; ceenu; chloroethylcyclohexylnitrosourea; cinu; cyclohexylchloroethylnitrosourea; icig1109; n-(2-chloroethyl)-n’-cyclohexyl-n-nitroso-ure; nci-c04740; nsc79037; nsc-79037; rb1509; 1-chloro-3-cyclohexyl-1-ethyl-3-nitrosourea |
Minimum assay |
≥98% |
Minimum stability |
|
Form |
yellow powder |
Solubility |
Soluble in ethanol (47 mg/ml at 25 °C), chloroform, water (<1 mg/ml at 25 °C), DMSO (47 mg/ml at 25 °C), and acetone. |
Application |
|
Usage |
a highly lipid soluble drug, treating brain tumors |
Melting point ca. |
88-90 ºC |
Boiling point ca. |
354.07 °C |
Density g/cm3 (20°C) |
1.31g/cm3 |
Refractive index |
1.57 |
Flash point |
133.2°C |
Stability |
Stable under recommended storage conditions |
Percent Composition |
C 46.25%, H 6.90%, Cl 15.17%, N 17.98%, O 13.69% |
Packaging |
required by customer |
Delivery Time |
overnight (USA/Canada); 3-5 days (worldwide) |
Storage |
Store at 4° C |
Transport information |
|
CAS NO:18472-51-0
CAS NO:6091-44-7
CAS NO:6091-44-7
CAS NO:6091-44-7
CAS NO:6091-44-7
CAS NO:6091-44-7
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