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1 Kilogram |
Negotiable |
Hyaluronic acid Sodium Hyaluronate Food Cosmetic additive
Product Descriptions
1,Product name: Sodium Hyaluronate
2,Other name: Hyaluronic Acid(HA) Sodium Salt
3,Cas no.: 9067-32-7
4,EINECS no.: 232-678-0
5,MF: C28H44N2O23.Na
Physical Properties
1,Appearance: white powder
2,Stable.Incompatible with strong oxidizing agents.
storage temp. | −20°C |
solubility | H2O: 5 mg/mL, clear, colorless |
Water Solubility | Soluble |
Merck | 134776 |
Specifications
/ | Cosmetic Grade | Food Grade | Medicine Grade | Low Molecule Grade |
Appearance | White Powder | White Powder | White Powder | White Powder |
Glucuronic Acid | ≥44% | ≥44% | ≥45% | ≥44% |
Molecular Weight(Dal) | (0.8-2.0)×106 | According to customer requirement | (0.8-2.0)×106 | According to customer requirement |
Protein | ≤0.1% | ≤0.1% | ≤0.05% | ≤0.1% |
Loss on Drying | ≤10.0% | ≤10.0% | ≤10.0% | ≤10.0% |
Residue on lgnition | < 20% | < 15% | <15%-20% | < 20% |
PH(0.1% Water Solution) | 6.0-7.5 | 6.0-7.5 | 6.0-7.5 | 6.0-7.5 |
Heavy Metal (as Pb) | < 10ug/g | < 10ug/g | < 10ug/g | < 10ug/g |
Arsenic | < 2ug/g | < 2ug/g | < 2ug/g | < 2ug/g |
Endotoxin | ------ | ------ | 1EU/mg | ------ |
Haemolysis | Negative | Negative | Negative | Negative |
Haemolytic streptococcus | Negative | Negative | Negative | Negative |
Total bacterica | < 100CFU/g | < 10CFU/g | < 10CFU/g | < 10CFU/g |
Other Indexes of Microorganism | According with National Standard | According with National Standard | According with National Standard | According with National Standard |
Applications
Application in the field of cosmetic
The amount of the additive HA in cosmetic is about 0.1%, and in special use its amount can be up to 0.5%. Higher molecular HA can be used in anti-wrinkle and sun-block creams, and its amount is about 0.1%~0.5%.
Due to its good penetration, lower molecular HA is widely used in cosmetic, and the amount of which is usually about 0.1%. For effective products such as sun-block and sunscreen the recommended HA amount is more
than 0.1%. HA can improve efficiency and prolong the expiration as its excellent sustained-release.
Application in the field of health food
HA is widely used in health food in western countries. At home and abroad health food(nutrition food )manufacturers often choose HA(800,000~1200,000Dalton) as additives to produce capsules and tablets. Low molecular weight HA is often added in oral liquid, oral powder and soft capsule due to its advantages such as good solubility, uniform mixture and excellent absorption.
When taken orally the concentration of HA in blood begins to increase rapidly after four hours, after twelve hours the HA concentration can get the maximum. When HA is continuously taken for 7 days, the HA concentration can keep steady.
Application in the field of medicine
HA can be used as viscoelastic agent in eye intraocular lens implant surgery, as filling agent in osteoarthritis and rheumatoid arthritis and other joint operation, as medium in eye drops and the prevention of postoperative adhesion and promoting the healing of skin wound, etc. HA with other drugs can act synergistically in drug slow release process, can play an important role in controlled drug release.
Package and Storage
Packaging Specifications | ||||
Category | Quantity per inner package | Inner package material | Quantity per outer package | Outer package |
Material | ||||
Powder | 1kg | LDPE bag+ Aluminium foil bag | 10kg,25kg/drum | Drum with polyethylene bag |
15kg,25kg/drum | ||||
5kg | LDPE bag+ Aluminium foil bag | 10kg,25kg/drum | Drum with polyethylene bag | |
100g | HDPE fluoride bottle | 1kg/box | Corrugated box | |
100g | Medicinal HDPE bottle Glass bottle | 1kg/box | Corrugated box with foam box | |
1% solution | 25kg | Fluoride drum | - | - |
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