High quality exemes...

High quality exemestane 99% cas NO:107868-30-4 lowest price

High quality exemestane 99% cas NO:107868-30-4 lowest price

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0 Metric Ton

FOB Price:USD 4000.0000 -4100.0000

  • Min.Order :0 Metric Ton
  • Purity: 99%
  • Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

cas:107868-30-4 exemestane Aromasin

Quick Details

  • Appearance:White crystalline powder
  • Application:API
  • PackAge:25Kg/drum,5KG/Aluminum foil bag,1KG/Aluminum foil bag
  • ProductionCapacity:|Metric Ton|Day
  • Storage:keep in cool and dried place
  • Transportation:by air/sea

Superiority:

Details:

Best quantity 99% Exemestane / Exemesta / Aromasin CAS:107868-30-4 Steroids Powder

 

 

Exemesta

1 CAS: 107868-30-4

2 Trade names: Aromasin

3 Formula: C20H24O2  

4 Mol. mass: 296.403 g/mol

5 Specification: Enterprise standard

 6 Appearance: white crystalline powder

 7 exemestane Assay: 99%

 

Applications:

High Purity Exemestane/Aromasin/Exemestan/CAS No: 107868-30-4

the third generation aromatase inhibitors, used in the treatment of metastatic breast cancer and used as aid in the treatment of early breast cancer.

Many breast cancers are stimulated to grow by the female sex hormones oestrogen and progesterone. These breast cancers are called hormone sensitive or hormone receptor positive and can be treated with drugs that block the effects of these hormones.

In women who have had their menopause, oestrogen is mainly produced by changing androgens (sex hormones produced by the adrenal glands) into oestrogens. This process is called aromatisation and happens mainly in the fatty tissues, muscle and the skin. It needs a particular enzyme called aromatase.

Exemestane blocks the process of aromatisation. So it lowers the amount of oestrogen in the body. In early breast cancer, taking exemestane can help to stop breast cancer coming back. In advanced breast cancer the cancer cells may grow more slowly or stop growing completely.

 

 

specification:

 

TEST ITEMS

       SPECIFICATION

RESULTS

Description

: White Crystalline Powder

White Powder

Identification

:  Positive

Positive

Assay(by HPLC)

:  98.0~102.0%

98.64%

Absorbance(E1cm)

:  465~495

482.5

Melting Point

:  191~195°C

193.5~195.0°C

Loss On Drying

:  0.5%max

0.19%

Specific Rotation

:  +288°~ +298°

+290.2°

Residue On Ignition

:  0.1%max

0.03%

Related Substances

:  Total:1.5%max

<1.3%

 

   Single:0.5%max

<0.4%

Residue Solvents

:  0.2%max

0.10%

Heavy Metals

:  20PPm max

<10PPm

 

 

 

Conclusion

The specification conform with enterprise standard.

 

 

 

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