- Min.Order :20 Kilogram
- Purity: 99%
- Payment Terms : L/C,D/A,D/P,T/T,Other
Keywords
Nicorandil 65141-46-0 White crystalline powder
Quick Details
- Appearance:White crystalline powder
- Application:API
- PackAge:As your needed
- ProductionCapacity:20|Kilogram|Quarter
- Storage:room temperature
- Transportation:SEA AIR
Superiority:
1, Full experience of large numbers containers loading in main Chinese seaports
2, Packing with pallet as buyer's special request
3, Best service after shipment with e-mail
4, Cargos together with container sales seervice available
5, Rich experience for exporting
6, Cargos photo before and after loading into container
7, Raw materials from chinese origin
8, Top Pharm Chemical Group(ISO 9001: 2008), are strong in the field of Pharmaceuticals,
food additives, plant extract and fine chemicals for more than 10 years.
Details:
| Nicorandil Basic information |
| Product Name: | Nicorandil |
| Synonyms: | n-[2-(nitroxy)ethyl]-3-pyridinecarboxamide;N-[2-(NITROOXY)ETHYL]-3-PYRIDINECARBOXAMIDE;NICORANDIL;PERISALOL;SIGMART;IKOREL;ADANCOR;2-nicotinamidoethylnitrate |
| CAS: | 65141-46-0 |
| MF: | C8H9N3O4 |
| MW: | 211.17 |
| EINECS: | 265-514-1 |
| Product Categories: | Pharmaceutical;Intermediates & Fine Chemicals;Pharmaceuticals;Potassium channel;Aromatics;Heterocycles;Ikorel;reagent;Cardiovascular APIs |
| Mol File: | 65141-46-0.mol |
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| Nicorandil Chemical Properties |
| mp | 92°C |
| storage temp. | Desiccate at +4°C |
| Safety Information |
| Nicorandil Usage And Synthesis |
| Chemical Properties | White solid |
| Usage | An antianginal |
| Usage | Antihypertensor |
| Biological Activity | K ATP channel opener and NO donor, clinically used as antianginal agent. Preferentially activates SUR2B- versus SUR2A-containing K ATP channels (EC 50 values are 10 and > 500 mM respectively) and causes 1.6-fold increase in cardiac eNOS expression. Displays coronary and peripheral vasodilatory properties, reduces both pre- and after-load, and increases coronary blood flow. Also displays cardioprotective effects, possibly through ischemic preconditioning. |
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