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Details:
CAS 64-75-5
Quick details:
Product name: Tetracycline hydrochloride
Chinese Synonyms: tetracycline hydrochloride; tetracycline hydrochloride; tetracycline hydrochloride capsules; hygromycin; tetracycline hydrochloride
CAS number: 64-75-5
EINECS number: 200-593-8
Molecular formula: C22H25ClN2O8
Molecular weight: 480.9
Assay: More than 95%
Related categories: antibiotics, alkaloids; antibiotic; raw material; tetracycline; analysis standards
Character: Yellow crystalline powder. MP 220-223 C. Alpha -252. Refractive index -253. Water soluble. pH of 2% aqueous solution: 2.1 - 2.3. Solubility H2O: 10 mg/mL as a stock solution. Stock solutions should be filtered sterilized and stored at 20C. Stable at 37C for 4 days.
Product description:
Tetracycline hydrochloride is a broad-spectrum antibiotics, high concentration has the sterilization effect, besides the common gram-positive bacteria, Gram-negative bacteria and anaerobic bacteria in Ji Lan, the majority of Rickettsia, mycoplasma, chlamydia, atypical mycobacterium, leptospirosis, actinomyces, anthrax, mononucleosis of bacteria Lester, Clostridium, Nocardia sensitive to the chemicals. This product is gram negative bacteria on leather effect is better than that of gram - positive bacterium, but Enterococcus and penicillin resistant Neisseria gonorrhoeae resistance to. The product of the Vibrio, Brucella, Campylobacter, Jerson bacteria and gram negative bacteria antibacterial effect, no antimicrobial activity against Pseudomonas aeruginosa.
Antibacterial mechanism is drug specific 30S subunit of the bacterial ribosome binding A location, connecting block aminoacyl tRNA in the position, thereby inhibiting growth peptide even and the influence of bacterial protein synthesis and produce antibacterial action, because it can change the bacterial cytoplasmic membrane permeability, so easily in the thallus accumulation, played fast inhibitory effect.