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Product Name: Norfloxacin hydrochloride
Synonym:
3-Quinolinecarboxylicacid, 1-ethyl-6-fluoro-1, 4-dihydro-4-oxo-7-(1-piperazinyl)-, hydrochloride(1:? ); 3-Quinolinecarboxylicacid, 1-ethyl-6-fluoro-1, 4-dihydro-4-oxo-7-(1-piperazinyl)-, hydrochloride(9CI); ;
Norfloxacin hydrochloride CAS No.: 104142-93-0
Norfloxacin hydrochloride Molecular formula: C16H18FN3O3. HCl
Norfloxacin hydrochloride Molecular weight: 355.79
Norfloxacin hydrochloride Assay: 98%
Norfloxacin hydrochloride Packing: 25KG/Drum
Norfloxacin hydrochloride Appearance: White powder
Norfloxacin hydrochloride Grade: Feed grade
Norfloxacin hydrochloride Category: Veterinary medicine
Norfloxacin hydrochloride Application:
Antimicrobial, used to treat infection of the upper respiratory tract, urinary system, gastrointestinal tract, also efficient to biliary tract, surgery and so on
Norfloxacin hydrochloride Pharmacological action:
This product is the main effect on the cell of DNA replication DNA gyrase subunit A process, blocking DNA replication, which inhibit the reproduction of bacteria to kill bacteria to.
1 direct interaction with pathogen nuclei, quickly and effectively kill the bacteria and Mycoplasma with DNA (or RNA) and protein synthesis ability of pathogens, and wide antimicrobial spectrum.
2 due to the destruction of the synthesis of nucleic acid, so that bacteria can not generate genetic information, so the cells to produce the mutation occurrence rate is low, no plasmid mediated resistance.
DNA gyrase DNA and bacterial pathogens of 3 different animal, the product is not sensitive, so the product of the high security.
This product absorbs quickly, quickly reach the peak plasma concentration, and the effective bactericidal concentration was maintained for a long time, against gram negative and gram positive bacteria is significant bactericidal effect at low concentration. Infection of good curative effect caused by Escherichia coli, Salmonella, Pseudomonas, bacillus, gram positive bacteria, the role of Staphylococcus aureus and other positive bacteria is very powerful. On the effects of Chicken Escherichia coli, Staphylococcus disease, pullorum disease, enteritis, fowl typhoid, avian paratyphoid. The enrofloxacin resistant strains are effective.
Usage and dosage
Livestock: Mixing the birds each 1000kg feed add norfloxacin (or salt) 100-200g, connect to use 3-5 days. Severe double.
The drinking bird per 1000kg of water added norfloxacin hydrochloride and norfloxacin nicotinate or norfloxacin lactate 50-100g, connect to use 3-5 days. Severe double.
Fisheries: Every 1000kg aquatic feed add norfloxacin (or salt) 150-300g, connect to use 5-7 days. Severe double.
Norfloxacin Hcl CAS 104142-93-0 Norfloxacin Hydrochloride
Norfloxacin Hcl CAS 104142-93-0 Norfloxacin Hydrochloride
Norfloxacin Hcl CAS 104142-93-0 Norfloxacin Hydrochloride
Norfloxacin Hcl CAS 104142-93-0 Norfloxacin Hydrochloride
Norfloxacin Hcl CAS 104142-93-0 Norfloxacin Hydrochloride
TEST | SPECIFICATION | RESULT | |
Description | White to pale yellow,hydroscpion, photosensitive,crystalline powder | Complies | |
Identification | IR | Complies | |
Appreance of solution | Complies | Complies | |
Related Substances | Impurity E | max.0.1% | 0.01% |
Methyl-Norfloxacin | max.0.15% | 0.08% | |
Unspecicifed Impurities | max.0.1% | 0.04% | |
Total Impurities | max.0.5% | 0.20% | |
Loss on drying | max.1.0% | 0.30% | |
Residue on ignition | max.0.1% | 0.05% | |
Heavy metals | max.15ppm | 10ppm | |
Purity | The sum of all impurities'peaks is not more than 0.5% | Complies | |
chromatographic | |||
Assay | 99.0%-101.0% | 99.80% | |
Residual Solvents Ethanol | max.5000ppm | Not detected |
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