99% High Quality Cosyntropin for Adrenocorticotropic Hormone (ACTH) CAS 12568-12-4 Powder

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Detailed Product Description 

99% High Quality Cosyntropin For Adrenocorticotropic Hormone (ACTH) CAS 12568-12-4 Powder 

Quick Detail: 

Cosyntropin 
Alias: ACTH (1-24), HUMAN; ACTH (1-24) (HUMAN, BOVINE, MOUSE, OVINE, PORCINE, RABBIT, RAT); ACTH (1-24); 
Purity: 99% 
CAS Registry Number: 16960-16-0 
Einecs No: 241-031-1 
Grade: Pharmceutical Grade 
Storage: Shading, confined preservation 
Usage: Cosyntropin (cortrosyn) is a synthetic derivative of adrenocorticotropic hormone (ACTH) that is used in the ACTH stimulation test to evaluate and diagnose cortisol disorders. 


Product description: 

MF: C136H210N40O31S 
MW: 2933.47 

Purity: 99% 
Melting point: 2 ° C 
Boiling point: 225° C 
Refractive index: 1.551-1.553 
Appearance: Colorless transparent liquid 


Application: 

In patients with low cortisol levels or symptoms of adrenocortical insufficiency, cosyntropin can be used to diagnose Addison's disease. A failure for serum cortisol levels to increase after administration of cosyntropin makes a diagnosis of primary adrenocortical insufficiency more likely. An increase in cortisol upon administration of cosyntropin rules out the condition. The test may also be used to assess the function of the adrenal glands after successful treatment for Cushing's syndrome. 
Cosyntropin is also used in the opposite situation, when there is aldosterone hypersecretion due to either a unilateral adrenal adenoma (which is treated by surgical removal) or bilateral adrenal hyperplasia. A procedure called adrenal venous sampling may be used pre-operatively to localize the source of aldosterone hypersecretion from either adrenal gland. A peripheral intravenous infusion of Cosyntropin before and during the procedure stimulates cortisol production and thereby verifies catheter position 


Specifications: 


Product name: Cosyntropin 
Appearance: Colorless transparent liquid 
Assay: 99% 
Molecular formula: C136H210N40O31S 
Molecular weight: 2933.47