Perospirone hcl Perospirone hcl powder Perospirone hcl price
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Its primary uses are in the treatment of schizophrenia and bipolar mania.[3][4]
In a clinical trial that compared it to haloperidol in the treatment of schizophrenia it was found to produce significantly superior overall symptom control. In another clinical trial perospirone was compared with mosapramine and produced a similar reduction in total PANSS score, except with respect to the blunted affect part of the PANSS negative score, in which perospirone produced a significantly greater improvement. In an open-label clinical trial comparing aripiprazole with perospirone there was no significant difference between the two treatments discovered in terms of both efficacy and tolerability. In 2009 a clinical trial found that perospirone produced a similar reduction of PANSS score than risperidone and the extrapyramidal side effects was similar in both frequency and severity between groups.
A meta-analysis published in 2013 found that it is statistically significantly less efficacious than other second-generation antipsychotics.
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