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Quick Detail:
Bivalirudin
Alias: Bivalirudin Trifluoroacetate
CAS No.: 128270-60-0
Grade: Pharmceutical Grade
Lead time: Within 2 days upon receipt of payment
Delivery time: 4-6 working days
Storage: A cool(2~8 º C) & dry place protected from light, keep package close when not in use.
Usage: Bivalirudin is a specific and reversible direct thrombin inhibitor (DTI).
Product description:
Molecular Formula: C98H138N24O33
Molecular Weight: 2180.33
Purity (HPLC): 98.0%min.
Appearance: White Powder
Single Impurity (HPLC): 1.0%max
Amino Acid Composition: ± 10% of theoretical
Peptide Content (N%): ≥ 80.0%
Water Content (Karl Fischer): ≤ 8.0%
TrifluoroAcetate Content(HPIC): ≤ 12.0%
MS (ESI): Consistent
Mass Balance: 95.0~105.0%
Application:
US (United States) Indications:
Bivalirudin is indicated for use as an anticoagulant in patients with unstable angina undergoing percutaneous transluminal coronary angioplasty (PTCA).
Bivalirudin with provisional use of glycoprotein IIb/IIIa inhibitor (GPI) is indicated for use as an anticoagulant in patients undergoing percutaneous coronary intervention (PCI).
Bivalirudin is indicated for patients with, or at risk of HIT/HITTS undergoing PCI.
Bivalirudin is intended for use with aspirin and has been studied only in patients receiving concomitant aspirin
EU (European) indications:
Percutaneous Coronary Intervention (PCI), including patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary PCI.
Bivalirudin is also indicated for the treatment of adult patients with unstable angina/non-ST segment elevation myocardial infarction (UA/NSTEMI) planned for urgent or early intervention.
Bivalirudin should be administered with aspirin and clopidogrel.
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