High Quality Somatostatin for Health Care CAS 38916-34-6

Details:

1. Quick Details:

Somatostatin
Alias: 15-28-Somatostatin-28, Synthetic cyclic release-inhibiting factor, Synthetic somatostatin-14
CAS No.: 38916-34-6
Molecular Formula: C76H104N18O19S2
Molecular Weight: 1637.88
Purity (HPLC): 98.0%min.
Appearance: White powder
Single Impurity (HPLC): 1.0%max
Amino Acid Composition: ± 10% of theoretical
Peptide Content (N%): ≥ 80.0%
Water Content (Karl Fischer): ≤ 8.0%
Acetate Content (HPIC): ≤ 15.0%
MS (ESI): Consistent
Specific Rotation (20/D): -37.0~-47.0° (c=1 1%HAc)
Mass Balance: 95.0~105.0%
Grade: Pharmaceutical Grade
Storage: Closed, below 2 ~ 8º C preservation
Usage: Somatostatin regulates insulin and glucagon, and regulates the endocrine system and affects neurotransmission and cell proliferation.

2. Description:

Somatostatin (also known as -inhibiting hormone (GHIH) or somatotropin release-inhibiting factor (SRIF)) or somatotropin release-inhibiting hormone is a peptide hormone that regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones. Somatostatin regulates insulin and glucagon.
Somatostatin has two active forms produced by alternative cleavage of a single preproprotein: One of 14 amino acids, the other of 28 amino acids.
In all vertebrates, there exist six different somatostatin genes that have been named SS1, SS2, SS3, SS4, SS5, and SS6. The six different genes along with the five different somatostatin receptors allows somatostatin to possess a large range of functions. Humans have only one somatostatin gene, SST.

3. Application:

Somatostatin (CAS No. 38916-34-6) is used as -release inhibiting factor; Treatment of severe, acute hemorrhage of gastroduodenal ulcers and experimental antidiabetic.
Chemical substances having a specific regulatory effect on the activity of a certain organ or organs. The term was originally applied to substances secreted by various ENDOCRINE GLANDS and transported in the bloodstream to the target organs. It is sometimes extended to include those substances that are not produced by the endocrine glands but that have similar effects.