High Purity Pharmaceutical Antibiotic Clindamycin Phosphate CAS 24729-96-2

Details:

1. Quick Detail:

Clindamycin phosphate
Synonym: U 28508; Dalacin-S
CAS No.: 24729-96-2
EINECE No.: 246-433-0
MF: C18H34ClN2O8PS
MW: 504.97
Assay ≥ 99.0%
Density: 1.41 g/cm3
Melting Point: 114 ° C
Refractive Index: 122 ° (C=1, H2O)
Water: Soluble in water
Solubilities: Soluble in water
Storage temp: 2-8° C
Appearance: White solid
Grade: Pharmaceutical Grade
Storage: Shading, confined preservation
Usage: Antibiotic


2. Product description:

Clindamycin is an antibiotic useful for the treatment of a number of infections. It is of the lincosamide class. It is usually used to treat infections with anaerobic bacteria, but can also be used to treat some protozoal diseases, such as malaria. It is a common topical treatment for acne and can be useful against some methicillin-resistant Staphylococcus aureus (MRSA) infections.


3. Application:

Clindamycin is used primarily to treat anaerobic infections caused by susceptible anaerobic bacteria, including dental infections, and infections of the respiratory tract, skin, and soft tissue, and peritonitis. In people with hypersensitivity to penicillins, clindamycin may be used to treat infections caused by susceptible aerobic bacteria, as well. It is also used to treat bone and joint infections, particularly those caused by Staphylococcus aureus. Topical application of clindamycin phosphate can be used to treat mild to moderate acne.
The use of clindamycin in conjunction with benzoyl peroxide is more effective in the treatment of acne than the use of either product by itself.
When testing a Gram-positive culture for sensitivity to clindamycin, it is common to perform a "D-Test" to determine if there is a macrolide-resistant subpopulation of bacteria present.
Given with chloroquine or quinine, clindamycin is effective and well tolerated in treating Plasmodium falciparum malaria; The latter combination is particularly useful for children, and is the treatment of choice for pregnant women who become infected in areas where resistance to chloroquine is common.
Clindamycin may be useful in skin and soft tissue infections caused by methicillin-resistant Staphylococcus aureus (MRSA).
The combination of clindamycin and quinine is the standard treatment for severe babesiosis.
Clindamycin may also be used to treat toxoplasmosis, and, in combination with primaquine, is effective in treating mild to moderate Pneumocystis jirovecii pneumonia.
The veterinary uses of clindamycin are quite similar to its human indications, and include treatment of osteomyelitis, skin infections, and toxoplasmosis, for which it is the preferred drug in dogs and cats. Toxoplasmosis rarely causes symptoms in cats, but can do so in very young or immunocompromised kittens and cats.