High Purity Pharmaceutical Raw Materials Ppi Lansoprazole CAS 103577-45-3

Details:

1. Quick Detail:

Lansoprazole
Synonym: 1h-benzimidazole, 2-(((3-methyl-4-(2, 2, 2-trifluoroethoxy)-2-pyridinyl)methyl)su; 2-(((3-methyl-4-(2, 2, 2-trifluoroethoxy)-2-pyridinyl)methyl)sulfinyl)-1h-Benz; Lfinyl)-; PREVACID; OGAST; LANSOPRAZOLE; LANSAPRAZOLE; LANSOX
InChI: InChI=1/C16H14F3N3O2S/c1-10-13(20-7-6-14(10)24-9-16(17, 18)19)8-25(23)15-21-11-4-2-3-5-12(11)22-15/h2-7H, 8-9H2, 1H3, (H, 21, 22)
Purity: 99%
CAS No.: 103577-45-3
Grade: Pharmaceutical Grade
Place of Origin: Wuhan, China
Delivery time: Usually 4-6 working days by air
Storage: Shading, confined preservation, 2-8° C
Usage: Lansoprazole is a proton-pump inhibitor (PPI) in the same pharmacologic class as omeprazole. Lansoprazole has been marketed for many years and is one of several PPIs available. Lansoprazole is a racemate 1: 1-mixture of the enantiomers dexlansoprazole (Dexilant, formerly named Kapidex) and levolansoprazole. Dexlansoprazole is an enantiomerically pure active ingredient of a commercial drug as a result of the 'enantiomeric shift'.


2. Product description:

MF: C16H14F3N3O2S
MW: 369.36
Assay ≥ 99.0%
Density: 1.5 g/cm
Melting Point: 178-182oC.
Boiling Point: 555.8oC at 760 mmHg
Vapour: 2.55E-10mmHg at 25° C
Refractive Index: 1.591
Flash Point: 289.9 oC
Solubilities: Insoluble
Storage temp: 2-8° C
Appearance: White Crystalline Powder


3. Indications

Lansoprazole is indicated for:
Treatment of ulcers of the stomach and duodenum, and NSAID-induced ulcers.
Adjunctive treatment of Helicobacter pylori infection, alongside antibiotics. Treatment to kill Helicobacter pylori (H. Pylori) causing ulcers or other problems involves using two other drugs besides lansoprazole. This treatment is known as "triple therapy", and involves taking twice daily for 10 or 14 days lansoprazole 30 mg, amoxicillin 1, 000 mg, and clarithromycin 500 mg.
Treatment of gastroesophageal reflux disease (GERD) (also known as acid reflux disease).
Treatment of Zollinger-Ellison Syndrome.