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Colistin Sulphate Colistin Sulphate Colistin Sulphate
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Quick Detail:
Colistin Sulphate:
CAS No.: 1264-72-8
Purity: 99%
MF: C52H98N16O13
Molecular Weight: 2801.27
Appearance: White powder
Effect: Cyclic polypeptide antibiotic produced by Bacillus polymyxa.
Description:
Colistin sulfate is a medication that has antibiotic properties, and is therefore often used to treat bacterial infections. A form of this compound is naturally produced by some bacteria in nature as a defense mechanism against other species. Its discovery LED to colistin becoming adapted for medicinal use. Only certain types of bacteria are affected by this drug, which is why it is generally taken for intestinal infections, and sometimes for infections on the surface of the skin.
Bacterial cell membranes have ions that help keep these barriers intact. Colistin sulfate can replace these ions, opening up the membrane and dissolving it. Liquids can then enter the affected bacterium, which destroy it. Variations in the ionic region of this medication have LED to two distinguishable forms of this drug, colistin sulfate and colistimethate sodium. Each of these compounds can be optimally effective against different species of germs.
Applications:
It is mainly used for sensitive bacteria infection, such as sepsis, acute enteritis and urinary tract infections, etc
Usually it is only used in last-resort situations, against germs that have proven to be resistant against other antibiotics.
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