17671-50-0 Betaine citrate C6H7O7.C5H12NO2
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1.Basic Information | ||||||||||||||||||
Product name: Betaine Citrate CAS No.: 17671-50-0 EINECS No.: 241-648-6 MF: C11H19O9N MW: 309.27 Appearance: White crystal or crystalline powder |
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2.Introduction |
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A betaine in chemistryis any neutral chemical compound with a positively charged cationic functional groupsuch as a quaternary ammonium or phosphoniumcation (generally: onium ions) which bears no hydrogen atom and with a negatively charged functional group such as a carboxylategroup which may not be adjacent to the cationic site. A betaine thus may be a specific type of zwitterion. Historically the term was reserved for trimethylglycine only. It is used as a medicine as well.
The correct pronunciation of the compound reflects its origin and first isolation from sugar beets, and does not derive from the Greek letter beta (β). However, it is often mispronounced beta-INE or even BEE-tayn.
In biological systems, many naturally occurring betaines serve as organic osmolytes, substances synthesized or taken up from the environment by cells for protection against osmoticstress, drought, high salinity or high temperature. Intracellular accumulation of betaines, non-perturbing to enzyme function, protein structure and membrane integrity, permits water retention in cells, thus protecting from the effects of dehydration. It is also amethyl donor of increasingly recognised significance in biology. |
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3.Specifications |
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5.Commercial uses |
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Phosphonium betaines are intermediates in the Wittig reaction. The addition of betaine to polymerase chain reactions improves the amplification of DNA by reducing the formation of secondary structure in GC-rich regions. The addition of betaine has been reported to enhance the specificity of the polymerase chain reaction by eliminating the base pair composition dependence of DNA melting. |
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