cas 80370-57-6 Ceftiofur Ceftiofur cas 80370-57-6
Name:Ceftiofur hydrochloride
CAS:103980-44-5
MF:C19H17N5O7S3.HCl
MW:560.03
Purity:98%
ceftiofur made in china
Appearance:White or yellowish powder.
Uses: veterinary antibiotics.
Day-old chicks for the prevention of early death and livestock gut, respiratory tract infections.
ITEMS |
SPECIFICATIONS |
RESULTS |
|
Appearance |
White to Off-white Crystalline powder |
Conform |
|
Identification |
The retention time of the principal peak in the chromatogram obtained with the test solution correspoonds to that of the principal peak in the chromatogram obtained with reference solution. |
Conform |
|
Reaction of Chloride |
Conform |
||
Appearance of solution |
Clarity |
Not stronger than No.1 Turbidity Standard |
<1 |
Color |
Not darker than standard solution Y9 |
<8 |
|
Solubility |
Soluble in N, N- Dimethylacetamide, slightly soluble in 5% of sodium bicarbonate and methanol. |
Conform |
|
PH |
2.0~3.0 |
2.2 |
|
Water Content |
1.5%~4.0% |
1.6% |
|
Specific optical Rotation |
-115°~-127° |
-117° |
|
Heavy metal |
NMT 0.0020% |
Conform |
|
Residue of ignition |
NMT 0.20% |
0.15% |
|
Related substances |
The biggest impurity |
NMT 0.20% |
0.09 |
Total impurities |
NMT 1.50% |
0.38 |
|
Residue solvents |
Ethyl Acetate |
NMT 0.5000% |
0 |
THF |
NMT 0.0720% |
0.006 |
|
Acetone |
NMT 0.5000% |
0.2739% |
|
Benzene |
NMT 0.0002% |
0.0001 |
|
Assay |
Ceftiofur Hydrochloride |
NLT 98.0% |
100.4% |
Chloride |
6.0%~6.5% |
6.2% |
|
Bacterial Endotoxin |
Less than 0.20EU/mg |
Conform |
|
Sterility |
Conforms the test |
Conform |
|
Particle size |
D (0,1) |
|
1.8 |
D (0,5) |
<4 |
1.4 |
|
D (0,9) <1 |
<7 |
3.7 |
|
D (1,0) |
<10 |
4.2 |
|
CONCLUSION |
THE TEST RESULTS CONFORMS TO THE SPECIFICATION |
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