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25 Kilogram |
Negotiable |
Paracetamol acetaminophen 103-90-2
acetaminophen manufacturers Specification:
Tests |
Standards |
Results |
|
Appearance |
White or almost white ,crystalline powder. |
White,crystalline powder. |
|
Identification |
A:IR absorption |
Complies |
Complies |
B:UV absorption |
Complies |
Complies |
|
C:TLC |
Complies |
Complies |
|
Melting point |
168~172°C |
169.0~170.9°C |
|
Water |
Not more than0.5% |
0.08% |
|
Related substance |
ImpurityJ(chloroacetanilide)not more than 10 ppm |
2ppm |
|
Impurity K(4-aminophenol)not more than 50 ppm |
15 ppm |
||
Impurity F(4-nitrophenol)not more than 0.05% |
Not detected |
||
any other impurity not more than 0.05% |
0.01% |
||
Total of other impurities not more than 0.1% |
0.02% |
||
Residue on ignition |
Not more than 0.1% |
0.05% |
|
Chloride |
Not more than 0.014% |
Less than 0.014% |
|
Sulfate |
Not more than 0.02% |
Less than 0.02% |
|
Sulfide |
Conforms |
Conforms |
|
Heavy metals |
Not more than 0.001% |
Less than 0.001% |
|
Free p-aminophenol |
Not more than 0.005% |
Less than 0.005% |
|
Limit of P-chloroacetanilide |
Not more than 0.001% |
Less than 0.001% |
|
Readily carbonizable substances |
Conforms |
Conforms |
|
Residual solvents |
Residual content of acetic acid is limited by the test of loss on dryingnot more than0.5% |
0.08% |
|
Assay(anhydrous basis) |
99.0~101.0% |
99.6% |
|
Conclusion: Complies with USP34/ BP2011 |
Appearance:
White crytallized powder, tasteless, soluble in water, ether, chloroform, etc
USES:Antipyretic analgesics
Acetaminophen, oral easy absorption. Its antipyretic and analgesic effects and aspirin similar, but antiphlogistic fights rheumatism role is very weak, the little sense. For gastrointestinal non-irritating, it doesn't cause coagulation disorders is its advantages. According to research, this drug resistance as well as the urea effect, can promote moisture absorption, again on urinary collapse disorder have certain curative effect. Often used to heat, cold, headache, muscle pain and neuropathic pain
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