High purity Spironolactone , CAS NO : 52-01-7
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| 1 Kilogram |
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- Min.Order :1 Kilogram
- Purity: >99.0%
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Spironolactone 52-01-7 Spironolactone manufacturer
Quick Details
- Appearance:White crystalline powder
- Application:API
- PackAge:25Kg/drum,5KG/Aluminum foil bag,1KG/Aluminum foil bag
- ProductionCapacity:|Metric Ton|Day
- Storage:keep in cool and dried place
- Transportation:by sea/air
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Chemical Name:Spironolactone
CAS No.:52-01-7
Synonyms:Dira;Altex;Acelat;Aldace;Osiren;Osyrol;sc9420;Alderon;Aldopur;Almatol
CBNumber:CB9743463
Molecular Formula:C24H32O4S
Formula Weight:416.57
MOL File:52-01-7.mol
| ITEMS | STANDARDS | RESULTS |
| Appearance (Ph.Eur.) | A white or yellowish-white powder | White powder |
| Solubility (Ph.Eur.) | Practically insoluble in water, soluble in ethanol (96%) | Complies |
| Identification | ||
| A. IR –spectrum (Ph.Eur.) | Meet the requirement | Complies |
| A. IR –spectrum (USP) | Meet the requirement | Complies |
| B. TLC (Ph.Eur.) | Meet the requirement | Complies |
| B. UV absorption (USP) | Meet the requirement | Complies |
| C. Colour reaction (Ph.Eur.) | Meet the requirement | Complies |
| C. Precipitate reaction (USP) | Meet the requirement | Complies |
| Specific optical rotation | -41°~-46° | -42.8° |
| (Ph.Eur.) | -41°~-45° | -42.9° |
| (USP) | ||
| Sulphated ash (Ph.Eur.) | ≤0.1% | 0.00% |
| Related substances (Ph.Eur.) | ||
| Impurity A | ≤0.2% | N.D. |
| Impurity B | ≤0.3% | N.D. |
| Impurity C | ≤0.2% | N.D. |
| Impurity D | ≤0.15% | N.D. |
| Impurity E | ≤0.3% | N.D. |
| Impurity I | ≤0.5% | 0.05% |
| Any unspecified impurity | ≤0.10% | Complies |
| Total | ≤0.7% | 0.13% |
| Ordinary impurities (USP) | ≤2.0% | Complies |
| Free thiol compounds (Ph.Eur.) | ≤0.05mL | Complies |
| Free mercapto compounds (USP) | ≤0.10mL | Complies |
| Chromium (Ph.Eur.) | ≤50ppm | Complies |
| Assay | 97.5%~102.0% | 100.90% |
| HPLC (Ph.Eur.) | 97.5%~103.0% | 99.60% |
| HPLC (USP) | ||
| Residual solvent (In-house) | ≤3000ppm | 90ppm |
| Methanol | ≤720ppm | ≤LOD (0.0046ppm) |
| Tetrahydrofuran | ≤880ppm | ≤LOD (0.23ppm) |
| DMF | ||
| Particle size (In-house) | 95% ≤ 20 microns | Complies |
| Conclusion |
Compiles with EP7/USP35 |
|
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