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Pregnenolone 145-13-1 Pregnenolone
Basic Information
Name: Pregnenolone
Chemical Name: 5- pregnen-3β- alcohol-20-one
Molecular Formula: C21H32O2
Molecular weight: 316.49
CAS#: 145-13-1
Appearance: white or almost white crystalline powder
Specification: 99%HPLC
Pregnenolone is a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens. As such it is a prohormone. Pregnenolone is a GABAA antagonist and increases neurogenesis in the hippocampus.Like other steroids, pregnenolone consists of four interconnected cyclic hydrocarbons. It contains ketone and hydroxyl functional groups, two methylbranches, and a double bond at C5, in the B cyclic hydrocarbon ring. Like all steroid hormones, it is hydrophobic. Its esterified version, pregnenolone sulfate, is water-soluble.
Application
1. Used in the synthesis of steroid drug intermediate and steroid drugs;
2. Used as intermediate for the synthesis of progesterone, antiflamison;
3. With the same function of corticosteroids anti-inflammatory.
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