- Min.Order :1 Kilogram
- Purity: ≥98%
- Payment Terms : L/C,D/A,D/P,T/T,Other
Keywords
Orlistat cas:96829-58-2 Orlipastat
Quick Details
- Appearance:White crystalline powder
- Application:API for loss weight
- PackAge:25Kg/drum,5KG/Aluminum foil bag,1KG/Aluminum foil bag
- ProductionCapacity:10|Metric Ton|Month
- Storage:keep in cool and dried place
- Transportation:by sea/air
Superiority:
Details:
| Test Items | Specifications |
| Specific Rotation | -48° ~ -51.0°(on the anhydrous, solvent-free basis) |
| Identification | A.HPLC: The retention time of the major peak of the sample solution corresponds to that of the standard solution. |
| B.IR: The IR spectrum of sample is consistent to the reference | |
| Related Substances | |
| Total impurity | Not more than 1.0% |
| Related Compound A | Not more than 0.2% |
| Related Compound B | Not more than 0.05% |
| Related Compound C | Not more than 0.05% |
| Related Compound D | Not more than 0.2% |
| Related Compound E | Not more than 0.2% |
| Formyl leucine | Not more than 0.2% |
| Orlistat open ring epimer | Not more than 0.2% |
| D-Leucine orlistat | Not more than 0.2% |
| Orlistat open ring amide | Not more than 0.1% |
| Individual unidentified impurity | Not more than 0.1% |
| Residual Solvents | |
| n-Hexane | Not more than 5000ppm |
| Isopropyl ether | Not more than 5000ppm |
| Residual on ignition | Not more than 0.1% |
| Heavy Metal | Not more than 20ppm |
| Water | Not more than 0.2% |
| Assay | 98.0%~101.5% (on the anhydrous, solvent-free basis) |
| Conclusion | Conform with USP35 |
Orlistat is used for the treatment of obesity.The amount of weight loss achieved with orlistat varies. In one-year clinical trials, between 35.5% and 54.8% of subjects achieved a 5% or greater decrease in body mass, although not all of this mass was necessarily fat. Between 16.4% and 24.8% achieved at least a 10% decrease in body mass.After orlistat was stopped, a significant number of subjects regained weight—up to 35% of the weight they had lost.
The incidence of type 2 diabetes in an obese population over four years is decreased with orlistat (6.2%) compared to placebo (9.0%).Long-term use of orlistat also leads to a modest reduction in blood pressure (mean reductions of 2.5 and 1.9 mmHg in systolic and diastolic blood pressure respectively).
Top Pharm Chemical Group is a regional, research ,industry and trade of hightech pharmaceutical chemical group .Headquartered in JiuLong Hong Kong . In recent years, through continuous integration, mergers and establish three domestic production base , now has its TOP Hanzhong plant extract production base , production base TOP Xi'an food additives , chemical intermediates production base TOP Taizhou .And China Marketing Center : Shaanxi TOP Pharm Chemical Co., Ltd. Sole responsibility for the TOP Group of each base , raw material supply factories , sales and import and export business ,providing thousands of plant extracts , food additives , feed additives , vitamin , pharmaceutical raw materials (API), chemical intermediates and other related customers worldwide products.
The company has advanced production equipment , perfect quality assurance system and perfect quality control system. Have multiple sets of high-pressure liquid chromatography, gas chromatography and ultraviolet spectrophotometer, such as efficient high-sensitivity analytical instruments, for the product of effective analysis and monitoring.To provide quality products , fast service is our final purpose , customer satisfaction is our relentless pursuit.
At Top Pharm, we firmly believe that customers' success is our success. Each staff member of our company is devoted to being ready for your requirements.
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