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Sitagliptin phosphate CAS NO.654671-78-0 Sitagliptin phosphate 654671-78-0
1.Product description
Product Name: Sitagliptin phosphate
CAS: 654671-78-0
MF: C16H15F6N5O.H3PO4
MW: 505.31
2.Physical properties
White or off white powder.Easy to dissolve in water
3.Specification
Item |
Requirements |
Test Results |
Description |
A white or almost white crystalline powder |
Complies |
High-performance liquid chromatograph HPLC |
The retention time of test sample major peak complies to reference standard |
Almost the same |
IR - Infrared spectrometry |
The retention time of test sample major peak complies to reference standard |
Almost the same |
Water |
≤1.0% |
0.20% |
Residue on ignition |
≤0.1% |
0.03% |
Sulphate |
≤0.02% |
Complies |
Chloride |
≤ 0.05% |
Complies |
Related impurity |
|
|
Total impurity |
≤ 1.0% |
0.06% |
Single impurity |
≤ 0.5% |
0.07% |
Chiral impurity |
≤ 0.5% |
0.11% |
Ethyl acetate |
≤ 0.5% |
0.10% |
Heavy metal |
≤ 20ppm |
<10ppm |
Assay |
≥99.0% |
99.9% |
Conclusion |
Meets the Requirements |
4.Application
A trizolopyrazine dipeptidyl peptidase IV inhibitor. It has recently been approved for the therapy of type II diabetes.
Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.
5.Packing
25KG/Drum or as per your requirement
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