99% Oxytocin CAS NO. 50-56-6 high purity oxytocin
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pharmaceutical intermediate
TEST | SPECIFICATION | RESULT | |
Appearance | White powder | Conform | |
Solubility | Soluble in water | Conform | |
Identity by HPLC | The retention is same with the reference substance | Conform | |
Acetate Content(By HPLC) | 6~10.0% | 7.50% | |
Peptide Purity (By HPLC) | ≧99.0% by area integration | 99.10% | |
Related Substance(By HPLC) | Total Impurities(%)≦1.0% | 0.90% | |
Largest Single Impurity(%)≦0.5% | 0.34% | ||
Water Content(Karl Fischer) | ≦5% | 4.70% | |
Organic solvent residue | Methanol≦0.3% | 0.21% | |
acetonitrile≦0.041% | 0.035% | ||
dichloromethane≦0.06% | 0.020% | ||
N,N-Dimethylformamide≦0.088% | 0.067% | ||
Specific Optical Rotation | —25.0°~—30.0° | -27° | |
pH value | 3.0~6.0 | 4.5 | |
Bacterial Endotoxins | ≦0.3EU | 0.22EU | |
Amino Acid Composition | Asp:0.9~1.10 | 1.00 | |
Glu:0.9~1.10 | 0.90 | ||
Gly:0.9~1.10 | 1.00 | ||
Pro:0.9~1.10 | 1.10 | ||
Ile:0.9~1.10 | 0.90 | ||
Leu:0.9~1.10 | 1.00 | ||
Tyr:0.9~1.10 | 1.10 | ||
Cys:1.4~2.1 | 1.80 | ||
Assay | 95.0%~105.0%(By Anhydrous, Acetic Acid-free ) | 99.80% |
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