Tamsulosin hydrochloride CAS:106463-17-6 TAMSULOSIN HCL
Tamsulosin hydrochloride
CAS Number: 106463-17-6
Molecular formula: C20H29ClN2O5S
It is is used in the treatment of difficult urination, a common symptom of enlarged prostate.
Attached is the COA for reference
Tests |
Specifications |
Results |
Appearance |
White or almost white crystalline powder, slightly soluble in water, freely soluble in formic acid, slightly soluble in anhydrous ethanol. |
Conformed |
Identification |
A: Should conformed B: Specific rotation: between -17.5 and -20.5° C: Examine by infrared absorption spectrophotometry, compare the spectrum obtained with reference spectrum should meet the requirement. D: Should conformed |
Conformed -19.0°
Conformed Conformed |
Melting point |
About 230°C |
233.1°C~233.5°C |
Loss on drying |
Not more than 0.5% |
0.03% |
Sulphated ash |
Not more than 0.1% |
0.02% |
Heavy metals |
Not more than 0.002% |
<0.002% |
Related substances Max single impurity Total impurities |
Not more than 0.1% Not more than 0.2% |
0.001% 0.019% |
Enantiomeric impurity |
Not more than 0.1% |
0.024% |
Assay |
98.5%~101.0% |
99.4% |
Residual solvents Ethanol |
Not more than 5000ppm |
400ppm |
Microbial limit test Total number of bacteria Number of molds |
Not more than 1000 cfu/gram Not more than 1000 cfu/gram |
10 cfu/gram 20 cfu/gram |
Conclusion |
Complies with EP 7.0 |
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