557795-19-4 Sinitinib cas:557795-19-4
Chemical Information
|
Molecular Weight (MW) |
398.47 |
Storage |
3 years -20℃powder |
|
Formula |
C22H27FN4O2 |
6 months-80℃in solvent |
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CAS No. |
557795-19-4 |
Synonyms |
Sunitinib, SU11248 |
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Solubility (25C) |
DMSO
|
Ethanol |
Water |
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79 mg/mL (198.25 mM)
|
13 mg/mL warmed (32.62 mM) |
<1 mg/mL (<1 mM) |
|||
<1 mg/ml means slightly soluble or insoluble. |
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Chemical Name |
(Z)-N-(2-(diethylamino)ethyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide |
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Description |
Sunitinib is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRβ with IC50 of 80 nM and 2 nM, and also inhibits c-Kit. |
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