Ribociclib cas 1211441-98-3

Min.Order / FOB Price:Get Latest Price

0 Metric Ton	Negotiable

0 Metric Ton

Negotiable

Min.Order :0 Metric Ton
Purity: 98%
Payment Terms : L/C

Keywords

1211441-98-3 Ribociclib cas 1211441-98-3

Quick Details

Appearance:Yellow Solid
Application:Inhibitor
PackAge:
ProductionCapacity:1|Kilogram|Month
Storage:
Transportation:

Superiority:

GMP factory

Packing with pallet as buyer's special request

Best service after shipment with e-mail

Cargos together with container sales seervice available

Api, inhibitor, and fine chemicals for more than 6 years.

Details:

Ribociclib, also known as LEE011, is an orally available cyclin-dependent kinase (CDK) inhibitor targeting cyclin D1/CDK4 and cyclin D3/CDK6 cell cycle pathway, with potential antineoplastic activity. CDK4/6 inhibitor LEE011 specifically inhibits CDK4 and 6, thereby inhibiting retinoblastoma (Rb) protein phosphorylation. Inhibition of Rb phosphorylation prevents CDK-mediated G1-S phase transition, thereby arresting the cell cycle in the G1 phase, suppressing DNA synthesis and inhibiting cancer cell growth. Overexpression of CDK4/6, as seen in certain types of cancer, causes cell cycle deregulation.

View All

Visit Store