Bortezomib 179324-69-7 Bortezomib
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Bortezomib Basic information
Product Name: | Bortezomib |
Synonyms: | VELCADE;dpba;BORTEZOMIB;[(1r)-3-methyl-1-[[(2s)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]-boronic acid;VELCADE(BORTEZOMIB);Boronic acid, B-[(1R)-3-methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]-;Bortezomib for research;Bortezomib ( Velcade, MG-341, PS-341 ) |
CAS: | 179324-69-7 |
MF: | C19H25BN4O4 |
MW: | 384.24 |
EINECS: | |
Product Categories: | Boron Derivatives;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Pepetides;ProteasomeInhibitors;Apis;Inhibitor;Final material;API;peptides |
Mol File: | 179324-69-7.mol |
Bortezomib Chemical Properties |
mp | 122-124°C |
density | 1.214 |
storage temp. | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
Stability: | Hygroscopic and Moisture Sensitive |
CAS DataBase Reference | 179324-69-7(CAS DataBase Reference) |
Safety Information |
Hazardous Substances Data | 179324-69-7(Hazardous Substances Data) |
Bortezomib Usage And Synthesis |
Chemical Properties | Yellow Solid |
Usage | Bortezomib is the first proteasome inhibitor to be approved b the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. T |
Usage | Bortezomib is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle foun d in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway. |
Usage | selective proteasome inhibitor |
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