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spiroxamine fungicide spiroxamine CAS No.:118134-30-8 spiroxamine 98%TC 50%EC 25%EC
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Toxicity:
Oral | Acute oral LD50 for male rats c. 595, female rats 500-560 mg/kg. |
Skin and eye | Acute percutaneous LD50 for male rats >1600, female rats c. 1068 mg/kg b.w. Severe skin irritant; not an eye irritant (rabbits). |
Inhalation | LC50 (4 h) for male rats c. 2772, female rats c. 1982 mg/m3. |
NOEL | (2 y) for rats 70, mice 160 mg/kg diet; (1 y) for dogs 75 mg/kg diet. |
ADI | 0.025 mg/kg b.w. |
Other | Not genotoxic; no specific effects on reproduction. |
Toxicity class | WHO (a.i.) II; EPA (formulation) II |
EC hazard | Xn; R20/21/22| Xi; R38| R43| N; R50, R53 |
Application:
Common name | Spiroxamine |
Formulation | Spiroxamine 98%TC, 25%+16.7%tebuconazole+4.3%triadimenolEC,80%EC |
Biochemistry | Sterol biosynthesis inhibitor, acting mainly by inhibition of D14-reductase. |
Mode of action | Protective, curative and eradicative systemic fungicide. Readily penetrates into the leaf tissue, followed by acropetal translocation to the leaf tip. Uniformly distributed within the whole leaf. |
Uses | Control of powdery mildew in cereals (Erysiphe graminis), at 500-750 g/ha, and in grapes (Uncinula necator), at 400 g/ha. Also gives good control of rusts (Rhynchosporium and Pyrenophora teres), together with certain side-effects against Septoria diseases. Penetration studies have shown that tank mixes of spiroxamine and triazoles can positively influence the uptake of triazoles in plants. |
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