CasNo.2627-69-2,AICAR 50mg peptides,(2627-69-2) Suppliers

100 Milligram	FOB Price: USD 100.0000

Min.Order :100 Milligram
Purity: 99%
Payment Terms : T/T,Other

Keywords

AICAR 50mg peptides AICAR 50mg peptides AICAR 50mg peptides

Quick Details

Appearance:liquid
Application:Peptides are used for -Burning Fats and lossing weight -Gaining mass (for example IGFs) - Body building -Anti aging (prevent wrinkles and prevent the body/skin from growing old or withering) -Mu
PackAge:Well packaged AND SEALED Professional Discreet packaging
ProductionCapacity:10000|Milligram |Day
Storage:room temperature
Transportation:AIR

Superiority:

USAGE

Peptides are used for

-Burning Fats and lossing weight

-Gaining mass (for example IGFs)

- Body building

-Anti aging (prevent wrinkles and prevent the body/skin from growing old or withering)

-Muscle strength and strong and resistant body and flesh

Reliable supplier since 2008

contact for more details on this products we are well edcuated vendors and business men/women with deep medical insights in what we sell and we can offer free consultation and councelling where and when neccessary.

Delivery period 2-3 days world wide Well packaged AND SEALED Professional Discreet packaging

Secure safe and swift delivery Reshipping if problem(Generally no susch problems or so called customs issues have ever occured with our shipments)

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with more than 7 years of experience we have the know how to get the best quality products for you

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Details:

AICAR

AICA-Ribonucleotide (AICAR)[edit] AICAR (5-amino-1-β-D-ribofuranosyl-imidazole-4-carboxamide), also known as ZMP, is an analog of AMP that is capable of stimulating AMP-dependent protein kinase activity (AMPK). AICAR is being researched to treat and protect against cardiac ischemic injury. If left untreated, it may lead to a myocardial infarct. Cardiac Ischemia is caused by insufficient blood flow and oxygen to the myocardium. AICAR was first used in the 1980s as a method to preserve blood flow to the heart during surgery.

Currently, AICAR has also been shown as a potential treatment for diabetes by increasing the metabolic activity of tissues by changing the physical composition of muscle. AICAR (commonly under the name Acadesine) is an analog of adenosine that enters cardiac cells to inhibit adenosine kinase and adenosine deaminase. It enhances the rate of nucleotide re-synthesis increasing adenosine generation from adenosine monophosphate only during conditions of myocardial ischemia. In cardiac myocytes, AICA-riboside is phosphorylated to AICA-ribotide (ZMP) to activate AMPK without changing the levels of the nucleotides. ZMP is able to enter the de novo synthesis pathway for adenosine synthesis to inhibit adenosine deaminase causing an increase in ATP levels and adenosine levels.

It has been shown that a brief period of coronary arterial occlusion followed by reperfusion prior to prolonged ischemia is known as preconditioning. It has been shown that this is protective. Preconditioning preceded myocardial infarction, may delay cell death and allow for greater salvage of myocardium through reperfusion therapy.

AICAR has been shown to precondition the heart shortly before or during ischemia.

AICAR triggers a preconditioned anti-inflammatory state by increasing NO production from endothelial nitric oxide synthase.

When AICAR is given 24 hours prior to reperfusion, it prevents post ischemic leukocyte-endothelial cell adhesive interactions with increased NO production.