BESTATIN

BESTATIN

BESTATIN

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1 Kilogram

Negotiable

  • Min.Order :1 Kilogram
  • Purity: 97%min
  • Payment Terms : L/C,D/A,D/P,T/T,

Keywords

58970-76-6 BESTATIN C16H24N2O4

Quick Details

  • Appearance:white powder
  • Application:diagnostic reagent
  • PackAge:meet the demand of customer
  • ProductionCapacity:|Metric Ton|Day
  • Storage:cold storage
  • Transportation:by sea or by air

Superiority:

good quality

Details:

Ubenimex Basic information
Product Name: Ubenimex
Synonyms: 3-(r)-amino-2-(s)-hydroxy-4-phenylbutanoyl-(s)-leucine;n-(3-amino-2-hydroxy-1-oxo-4-phenylbutyl)-,(s-(r*,s*))-l-leucin;nk421;UBENIMEX;N-[(2S,3R)-3-AMINO-2-HYDROXY-1-OXO-4-PHENYLBUTYL]-L-LEUCINE;N-((2S,3R)-3-AMINO-2-HYDROXY-4-PHENYLBUTYRYL)-L-LEUCINE;[(2S,3R)-3-AMINO-2-HYDROXY-4-PHENYLBUTYRYL]-L-LEUCINE;[(2S,3R)-3-AMINO-2-HYDROXY-4-PHENYLBUTANOYL]-LEU
CAS: 58970-76-6
MF: C16H24N2O4
MW: 308.37
EINECS: 261-529-2
Product Categories: Active Pharmaceutical Ingredients;Ubenimex;Pepetides;ProteaseInhibitors;peptides;Bestatin
Mol File: 58970-76-6.mol
Ubenimex Structure
 
Ubenimex Chemical Properties
mp  245 °C (dec.)(lit.)
storage temp.  2-8°C
Merck  13,9910
CAS DataBase Reference 58970-76-6(CAS DataBase Reference)
 
Safety Information
Safety Statements  22-24/25
WGK Germany  3
RTECS  OH2915000
MSDS Information
Provider Language
Ubenimex English
ACROS English
SigmaAldrich English
 
Ubenimex Usage And Synthesis
Chemical Properties white powder
Usage Ubenimex is a competitive aminopeptidase B inhibitor with an IC50 of 100 mg/ml for K562 cells. Proliferation of all the cell lines except KG1 was inhibited by bestatin. P39/TSU, HL60 and U937 were highly sensitive, with 50% growth inhibitory concentration
Usage Bestatin is "pseudo"-dipeptide isolated from Strepotmyces olivreticuli in 1976. Bestatin is a potent aminopeptidase B inhibitor with no carboxypeptidase activity. Bestatin acts as an immunomodulator by activating macrophages and T lymphocytes. Bestatin also exhibits good antitumour activity and is has been investigated in clinical trials.
Usage Bestatin is "pseudo"-dipeptide isolated from Streptomyces olivreticuli in 1976. Bestatin is a potent aminopeptidase B inhibitor with no carboxypeptidase activity. Bestatin acts as an immunomodulator by activating macrophages and T lymphocytes. Bestatin also exhibits antitumor activity and has been investigated in clinical trials.
Biological Activity Aminopeptidase inhibitor (K i = 0.001-90 mM); inhibits enkephalin metabolism and leukotriene A 4 hydrolase. Inhibits tumor cell proliferation.
 
Ubenimex Preparation Products And Raw materials
 

 

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