- Min.Order :1 Kilogram
- Purity: 98%
- Payment Terms : L/C,D/A,D/P,T/T,
Keywords
184475-35-2 Gefitinib C22H24ClFN4O3
Quick Details
- Appearance:White or off-white Solid
- Application:Organic synthesis
- PackAge:According to the demand of customer
- ProductionCapacity:20|Metric Ton|Month
- Storage:Sealed, dry, microtherm , avoid light and smell.
- Transportation:by air or by sea
Superiority:
high quality
Details:
| Gefitinib Basic information |
| Product Name: | Gefitinib |
| Synonyms: | IRESSA;GEFITINIB;AKOS 91371;n-(3-chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine;N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine;ZD 1839;4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-;Gefitinib(TINIBS) |
| CAS: | 184475-35-2 |
| MF: | C22H24ClFN4O3 |
| MW: | 446.9 |
| EINECS: | |
| Product Categories: | Active Pharmaceutical Ingredients;Gefitinib;Molecular Targeted Antineoplastic;Intermediates & Fine Chemicals;Pharmaceuticals;Pharmaceutical intermediate;APIs;IRESSA;Anti-cancer&immunity;API |
| Mol File: | 184475-35-2.mol |
|
|
|
| Gefitinib Chemical Properties |
| mp | 119-1200C |
| storage temp. | Store at RT |
| CAS DataBase Reference | 184475-35-2(CAS DataBase Reference) |
| Safety Information |
| Gefitinib Usage And Synthesis |
| Chemical Properties | Light-Yellow Crystalline Powder |
| Usage | Gefitinib (Iressa, ZD-1839) is an EGFR inhibitor for Tyr1173, Tyr992, Tyr1173 and Tyr992 in the NR6wtEGFR and NR6W cells with IC50 of 37 nM, 37nM, 26 nM and 57 nM, respectively. |
| Usage | Gefitinib is an antineoplastic. |
| Biological Activity | Orally active, selective inhibitor of EGFR tyrosine kinase (IC 50 = 23-79 nM). Shows minimal activity against ErbB2, KDR, c-flt, PKC, MEK and ERK-2. Blocks EGFR autophosphorylation and inhibits tumor growth in mice bearing a range of human xenografts. |
|
Gefitinib Preparation Products And Raw materials |
You Might Also Like
-
3164-13-4, 2-(4-BROMO-PHENYL)-BENZOOXAZOLE
CAS NO:3164-13-4
-
(1R,2S,5R)-5-Methyl-2-isopropylcyclohexyl 5-oxo-L-prolinate
CAS NO:64519-44-4
-
2,5-Dihydroxybenzaldehyde
CAS NO:1194-98-5
-
4-AMINOBIPHENYL
CAS NO:92-67-1
-
Phenol, 2-(4,6-diphenyl-1,3,5-triazin-2-yl)-5-methoxy-
CAS NO:106556-36-9
-
N,N'-dimethyl-N-[2-(methylamino)ethyl]ethylenediamine
CAS NO:105-84-0
Related Searches
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View