- Min.Order :1 Kilogram
- Purity: 98%
- Payment Terms : L/C,D/A,T/T
Keywords
284461-73-0 Sorafenib tosylate C21H16ClF3N4O3
Quick Details
- Appearance:White or off-white Solid
- Application:Organic synthesis
- PackAge:According to the demand of customer
- ProductionCapacity:20|Metric Ton|Month
- Storage:Sealed, dry, microtherm , avoid light and smell.
- Transportation:by air or by sea
Superiority:
high quality
Details:
| Sorafenib tosylate Basic information |
| Product Name: | Sorafenib tosylate |
| Synonyms: | sorafenib;SORAFENIB-D3;SORAFENIB TOLSYLATE;RAF1 KINASE INHIBITOR II;N-(4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL)-((4-(2-(N-METHYL-CARBAMOYL)(4-PYRIDYLOXY))PHENYL)AMINO)CARBOXAMIDE;4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-n-methyl-pyridine-2-carboxamide;BAY 43-9006;SORAFENIB MESYLATE |
| CAS: | 284461-73-0 |
| MF: | C21H16ClF3N4O3 |
| MW: | 464.83 |
| EINECS: | |
| Product Categories: | Sorafinib;Molecular Targeted Antineoplastic;All Inhibitors;anti-neoplastic;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Pharmaceutical intermediate;Amines;Inhibitor;Bay 43-9006 |
| Mol File: | 284461-73-0.mol |
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| Sorafenib tosylate Chemical Properties |
| mp | 202-204°C |
| storage temp. | -20°C Freezer |
| CAS DataBase Reference | 284461-73-0(CAS DataBase Reference) |
| Safety Information |
| Sorafenib tosylate Usage And Synthesis |
| Chemical Properties | Light Yellow Solid |
| Usage | A potent RAF kinase inhibitor. Antineoplastic |
| Usage | Multiple kinase inhibitor targeting both RAF kinase and receptor tyrosine kinases that promote angiogensis. Antineoplastic. |
| Usage | Sorafenib Tosylate (Bay 43-9006, Nexavar) is a small molecular inhibitor of VEGFR, PDGFR, c-Raf and B-Raf with IC50s of 18 nM, 10 nM, 3 nM and 15 nM, respectively. |
| Usage | Sorafenib Tosylate (Bay 43-9006) is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively - See more at: # |
| Sorafenib tosylate Preparation Products And Raw materials |
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