- Min.Order :1 Kilogram
- Purity: 98%
- Payment Terms : L/C,D/A,D/P,T/T,
Keywords
667463-62-9 6BIO C16H10BrN3O2
Quick Details
- Appearance:white powder
- Application:Organic synthesis
- PackAge:According to the demand of customer
- ProductionCapacity:1|Metric Ton|Month
- Storage:Sealed, dry, microtherm , avoid light and smell.
- Transportation:by air or by sea
Superiority:
high quality
Details:
| BIO Basic information |
| Product Name: | BIO |
| Synonyms: | 2H-Indol-2-one, 6-broMo-3-[(3E)-1,3-dihydro-3-(hydroxyiMino)-2H-indol-2-ylidene]-1,3-dihydro-, (3Z)-;6BIO;6-bromoindirubin-3-oxime |
| CAS: | 667463-62-9 |
| MF: | C16H10BrN3O2 |
| MW: | 356.178 |
| EINECS: | |
| Product Categories: | Intracellular Signaling;Inhibitors |
| Mol File: | 667463-62-9.mol |
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| BIO Chemical Properties |
| storage temp. | 2-8°C |
| solubility | DMSO: >5 mg/mL |
| form | solid |
| color | dark red |
| BIO Usage And Synthesis |
| Biological Activity | Potent and selective, ATP-competitive glycogen synthase kinase-3 (GSK-3) inhibitor (IC 50 values are 5, 83, 300, 320 and > 10 000 nM at GSK-3, CDK5/p25, CDK2/cyclin A, CDK1/cyclin B and other common kinases respectively). Maintains self-renewal and pluripotency in embryonic stem cells via activation of the Wnt signaling pathway in vitro . |
| BIO Preparation Products And Raw materials |
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