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137076-22-3 1-(tert-Butoxycarbonyl)-4-piperidinecarboxaldehyde C11H19NO3
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1-tert-Butoxycarbonyl-4-piperidinecarboxaldehyde Basic information |
Product Name: | 1-tert-Butoxycarbonyl-4-piperidinecarboxaldehyde |
Synonyms: | 4-FORMYL-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;1-BOC-4-PIPERIDINECARBOXALDEHYDE;1-BOC-4-FORMYLPIPERIDINE;1-TERT-BUTOXYCARBONYLPIPERIDINE-4-CARBOXYL ALDEHYDE;1-N-BOC-4-FORMYLPIPERIDINE;N-BOC-4-PIPERIDINYLCARBOXALDEHYDE;N-BOC-4-FORMYLPIPERIDINE;1-N-Boc-4-piperidinecarboxaldehyde |
CAS: | 137076-22-3 |
MF: | C11H19NO3 |
MW: | 213.27 |
EINECS: | |
Product Categories: | Carbonyl Compounds;Heterocycles;pharmacetical;Piperidine;Aldehydes;Pyrans, Piperidines & Piperazines;Inhibitors;Building Blocks;C10-C12;C11;Chemical Synthesis;Heterocyclic Building Blocks;Organic Building Blocks;Piperidines |
Mol File: | 137076-22-3.mol |
1-tert-Butoxycarbonyl-4-piperidinecarboxaldehyde Chemical Properties |
mp | 34-40℃ |
storage temp. | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
CAS DataBase Reference | 137076-22-3(CAS DataBase Reference) |
Safety Information |
Hazard Codes | Xi,N,Xn |
Risk Statements | 36/37/38-50-22 |
Safety Statements | 26-36/37/39-61 |
RIDADR | UN 3077 9/PG 3 |
1-tert-Butoxycarbonyl-4-piperidinecarboxaldehyde Usage And Synthesis |
Chemical Properties | Clear Yellow Oil |
Usage | Reactant for synthesis of:• ;Pim-1 inhibitors1• ;Selective GPR119 agonists for type II diabetes2• ;M-tropic (R5) HIV-1 replication inhibitors3• ;HDAC inhibitors4• ;Selective 5-HT6 antagonists5Reactant for three-component vinylogous Mannich reactions6 |
Usage | An intermediate for polycyclic indazole derivatives that are ERK inhibitors. |
1-tert-Butoxycarbonyl-4-piperidinecarboxaldehyde Preparation Products And Raw materials |
Raw materials | Dichloromethane-->Lithium aluminium hydride-->Di-tert-butyl dicarbonate-->Sodium acetate-->Manganese dioxide-->Pyridinium chlorochromate-->Isonipecotic acid-->4-Piperidinemethanol |
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