ABT-263 (Navitoclax)

ABT-263 (Navitoclax)
ABT-263 (Navitoclax)

ABT-263 (Navitoclax)

Min.Order / FOB Price:Get Latest Price

1 Kilogram

Negotiable

  • Min.Order :1 Kilogram
  • Purity: 98%
  • Payment Terms : L/C,D/A,D/P,T/T,

Keywords

923564-51-6 ABT-263 (Navitoclax) C47H55ClF3N5O6S3

Quick Details

  • Appearance:White or off-white Solid
  • Application:Organic synthesis
  • PackAge:According to the demand of customer
  • ProductionCapacity:20|Metric Ton|Month
  • Storage:Sealed, dry, microtherm , avoid light and smell.
  • Transportation:by air or by sea

Superiority:

T he company has advanced technology, as well as a large number of excellent R & D team, to provide customers from the grams to one hundred kilograms and tons of high-quality products, competitive prices and quality service

 

Details:

 Located in Zhengdong New District, Zhengzhou of Henan province, Henan Allgreen Chemical Co.,Ltd is comprehensive high-tech modern enterprises integrating professional R&D, production and sales.  Strong technical force, with a long-term professional development team engaging in the fine chemicals, Henan Allgreen Chemical Co.,Ltd is mainly engaged in development and customized of organic electronic chemical materials, metal catalysts, phosphorus ligands, medical intermediate , chemical reagent and other fine chemical products.We have multifunctional production conditions and could offer high quality products from grams to kilograms and tons. In addition, we absorb new technology actively from colleges and also have established good relations of cooperation with Huazhong University of Science and Technology ,Henan Institute of Engineering and some other well-known domestic enterprises.  Our products have been exported to Japan, South Korea, Europe, America and other countries and regions, well received by customers.        

  With sound management system, we've been authorized the Import&Export qualification by the government and also has passed the “ISO 9001-2008 Quality Management System” certification. We always stand on the quality of product as our life, develop in the direction of customers requirement and aim at creating greater value for customers.Innovation and honesty, we will make common development with the masses of customers at home and abroad hand in hand by our best service.

ABT 263 Basic information
Product Name: ABT 263
Synonyms: 4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide;ABT 263;Benzamide, 4-(4-((2-(4-chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl)methyl)-1-piperazinyl)-N-((4-(((1R)-3-(4-morpholinyl)-1-((phenylthio)methyl)propyl)amino)-3-((trifluoromethyl)sulfonyl)phenyl)sulfonyl)-;ABT-263,Navitoclax;Navitoclax;BenzaMide, 4-(4-((2-(4-chlorophenyl)-5,5-diMe;Navitoclax (ABT-263);(S)-4-(4-((4'-chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((4-((4-morpholino-1-(phenylthio)butan-2-yl)amino)-3-((trifluoromethyl)sulfonyl)phenyl)sulfonyl)benzamide
CAS: 923564-51-6
MF: C47H55ClF3N5O6S3
MW: 974.61
EINECS:  
Product Categories: Chiral Reagents;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;Apis;Inhibitor
Mol File: 923564-51-6.mol
ABT 263 Structure
 
ABT 263 Chemical Properties
Melting point  114-116°C
storage temp.  -20°C Freezer, Under Inert Atmosphere
 
Safety Information
MSDS Information
 
 
ABT 263 Usage And Synthesis
Chemical Properties Pale Yellow Solid
Usage ABT-263 (Navitoclax) is a potent inhibitor of Bcl-xL, Bcl-2 and Bcl-w with Ki of ≤ 0.5 nM, ≤1 nM and ≤ 1 nM, respectively.
Usage A novel inhibitor of antiapoptotic BCL-2 proteins; a new promising anticancer drug candidate.
 
ABT 263 Preparation Products And Raw materials
 

 

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