Esomeprazole sodium...

Esomeprazole sodium China manufacture 99%min

Esomeprazole sodium China manufacture 99%min

Min.Order / FOB Price:Get Latest Price

1 Kilogram

Negotiable

  • Min.Order :1 Kilogram
  • Purity: ≥99.0%
  • Payment Terms : L/C,D/A,D/P,T/T,,Other

Keywords

Esomeprazole sodium ESOMEPRAZOLE SODIUM 1H-BENZIMIDAZOLE, 5-METHOXY-2-[[(4-METHOXY-3,5-DIMETHYL-2-PYRIDINYL)METHYL]SULFINYL]-, SODIUM SALT

Quick Details

  • Appearance:White or off-white powder
  • Application:used for medicine
  • PackAge:Packaging according to customer requirements
  • ProductionCapacity:|Metric Ton|Day
  • Storage:Room temperature preservation
  • Transportation:by sea by air express

Superiority:

USP standard

Details:

 

Description

White to an off-white powder ;hygroscopic in nature 

Solubility  

Freely soluble in water ,soluble in propylene glycol;sparingly soluble in alcohol and methanol 

 Identification by

 
  1. UV：0.002% solution in 0.1m NaOH exhibits absorption maximum at 305nm and 276nm and the ratio is 1.6 to1.8
  2. IR：the IR spectrum should be concordant with the IR spectrum of the working standard
  3. Test for sodium： the residue on ignition gives reaction of sodium

Appearance of solution

(2.0 % w/v aqueous solution )

Should be clear

PH

(2.0 % w/v aqueous solution )

10.3 to 11.3

Water by KF (%w/w) 

NMT 6.0%

Specific Rotation at 25 ℃(1.0% w/v solution in methanol)

-38 °~ –48.0°

Heavy metals as pb

NMT20ppm

 Purity and related substances by HPLC (%)

 

a) Purity  NLT 99.5%

b) Total impurities NMT 0.5%

c) individual impurity NMT 0.2%

Assay by HPLC (% w/w)

(On Anhydrous Basis)

98.0 % to 102.0%

Residual Solvents by GC-HS (ppm)

 

a) Methylene Chloride NMT 600ppm

b) Methanol NMT 3000ppm

c) Ethyl Acetate NMT 5000ppm

d) Toluene NMT 890ppm

 

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