sorafenib

sorafenib
sorafenib
sorafenib
sorafenib
sorafenib

sorafenib

Min.Order / FOB Price:Get Latest Price

1000 Gram

FOB Price: USD 9000.0000

  • Min.Order :1000 Gram
  • Purity: 99.5（%）
  • Payment Terms : L/C,T/T,

Keywords

284461-73-0 sorafenib Nexavar; NEXAVAR; BAY-43-900; Sorafenib; SORAFENIB TOLSYLATE;

Quick Details

  • Appearance:appearance White powder
  • Application:Widely used in cosmetics, medicine, beauty health food and other industries
  • PackAge:1000 g/aluminum foil bag
  • ProductionCapacity:10|Metric Ton|Month
  • Storage:Dry and ventilated
  • Transportation:shipping

Superiority:

chengdu and import and export trade co., LTD., who registered capital of 10 million yuan, nearly  to $2 million, we  have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and development production of reagent tens of thousands of species. our aim is quality strives for the survival. Seek development by credit reputation. Our products have big price advantage in Europe South America and so on .and Our company also  has the advantage of high quality in Africa. in the past two years our products  has reached more than 30 countries in the world, Europe. South America. North America, southeast Asia, Africa, etc. We welcome all over the world with the best quality and lowest price friend common cooperation and common development!The quality of our products meet all international standards, the German advanced equipment are imported equipment two laboratories, individual, on scale management concept, our aim is;With the highest quality. The lowest price. The best service to meet the new and old customers around the world, develop together for a better future!

Details:

Chinese name: sorafenib Chinese alias: Raf inhibitor.4 - {4 - [3 - (4 - chlorine - 3-3 methyl phenyl) ureide] phenoxy} pyridine - 2 - formamide;Sola fini;English name: sorafenib English alias: Nexavar;NEXAVAR;BAY - 43-900;Sorafenib.SORAFENIB TOLSYLATE;Read more English nickname CAS no. : 284461-73-0 formula: C21H16ClF3N4O3 molecular weight: 464.82500 the precise quality: 464.08600 PSA: LogP 92.35000:6.08660Keywords

  • Sorafenib 99% supplier
  • 284461-73-0 high purity
  • cas 284461-73-0 factory

Quick Details

  • ProName: Sorafenib
  • CasNo: 284461-73-0
  • Appearance: white powder
  • Application: api
  • DeliveryTime: 5-7days
  • PackAge: aluminous bag
  • Port: shanghai
  • ProductionCapacity: 1000 Metric Ton/Day
  • Purity: 99%
  • Storage: sgading, sealed, dry place
  • Transportation: sea or air
  • LimitNum: 1 Metric Ton
  • Moisture Content: 0.25%
  • Impurity: 0.3%
  • Tadalafil: good quality
  • soluble: volatile

Superiority

 

Our Services

 Guaranteed & Quality control:  

1. The COA, NMR, HPLC and MSDS. 
2. 30days free return.

3. Chemists always available to discuss your needs.

Custom Synthesis Services:

We make our efforts to offer customer innovative, customized, high-quality service. 
Our custom manufacturing encompasses everything from pharmaceutical intermediates to API.

 

 

Details

  • ProName: Sorafenib
  • CasNo: 284461-73-0
  • Appearance: White Solid
  • Application: Research and development in pharmaceut...
  • DeliveryTime: Within 3 days after receive payment
  • PackAge: Sealed aluminum foil package or PTFE b...
  • Port: Shanghai port
  • ProductionCapacity: 100 Kilogram/Month
  • Purity: 98%
  • Storage: cool and dry place
  • Transportation: By courier/ By air
  • LimitNum: 5 Milligram
  • Related Substances: Not available
  • Residue on Ignition: Not available
  • Heavy Metal: Not available
  • Valid Period: One year

Details

 

(1) Company profile

 

Company name:                  Zhejiang J&C Biological Technology Co., Limited 

 

Year established:                2009 

 

Main products:                    Pharmaceutical intermediate: heterocycles series contains pyridine,boric      

                 

                                          acid,pyrazine,pyrazole,  Thiazole and so on

 

                                          API: anti-caner, antivirus, antihypertensive

 

                                          OLED production

 

(2) Product

 

 

Name

Sorafenib

Appearance

white powder

Capacity

200kg/year

Application:

anti-cancer pharmaceutical

Package

1kg/bag

Assay

≥99%

Standard:

enterprise

Manufacture

WEDOCHEM

Molecular Formula

C21H16ClF3N4O3

Molecular Weight

464.83

 

(3)  Application
 

    Sorafenib is a kind of new multiple targets anti-tumor drugs. It applies to tumor cells and blood vessels at the same

 

time. It is a RAF kinase inhibitor which suppresses ERK phosphorylation. Studies indicate that Sorafenib induces c-Raf

 

phosphorylation at both Ser-43 and Ser-259. When combined with vitamin K1 phosphorylation is increased at these

 

serine residues. Sorafenib also induces the phosphorylation of PKA. In addition, Sorafenib induces c-Met

 

phosphorylation at Tyr-1349, which consequently induces PI3K-Akt phosphorylation. Studies determined that Sorafenib

 

inhibits other kinases such as Flk-1 (VEGFR2), platelet-derived growth factor receptor (PDGFR), FLT3, Ret, and c-

 

Kit.          

 

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