Lomustine /cas:1301...

Lomustine /cas:13010-47-4
Lomustine /cas:13010-47-4

Lomustine /cas:13010-47-4

Min.Order / FOB Price:Get Latest Price

0 Metric Ton

Negotiable

  • Min.Order :0 Metric Ton
  • Purity: ≥98%
  • Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

treating brain tumors belustine Api-lomustine

Quick Details

  • Appearance:yellow powder.
  • Application:Lomustine is an alkylating nitrosourea compound used in chemotherapy.
  • PackAge:lastic bucket,25kg/package,200KG/package
  • ProductionCapacity:3|Metric Ton|Month
  • Storage:Store in a tightly closed container
  • Transportation:by air/sea

Superiority:

Superiority:

Aopharm is specialized in APIs, pharmaceutical intermediates & fine chemicals.

1. The best quality, competitive price.

2. The best service before or after shipment.

3. Rich experience in export operation.

4. Rich experience in modes of transportation.

5. Professional sale staff with chemical knowledge.

6. Full protecting of our customers’ profit.

Details:

Formula

C9H16CIN3O2

Molecular weight

233.70

EINECS

235-859-2

CAS RN

 13010-47-4

CAS Name

 

Synonyms:

1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea; (chloro-2-ethyl)-1-cyclohexyl-3-nitrosourea; (cloro-2-etil)-1-cicloesil-3-nitrosourea; 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosoure; 1-(2-chloroethyl)-3-cyclohexyl-1-nitroso-ure; belustine; cecenu; ceenu; chloroethylcyclohexylnitrosourea; cinu; cyclohexylchloroethylnitrosourea; icig1109; n-(2-chloroethyl)-n’-cyclohexyl-n-nitroso-ure; nci-c04740; nsc79037; nsc-79037; rb1509; 1-chloro-3-cyclohexyl-1-ethyl-3-nitrosourea

Minimum assay

 ≥98%

Form

yellow powder

Solubility

Soluble in ethanol (47 mg/ml at 25 °C), chloroform, water (<1 mg/ml at 25 °C), DMSO (47 mg/ml at 25 °C), and acetone.

Application 

 Lomustine is clinically used to treat various forms of cancer.

Usage

a highly lipid soluble drug, treating brain tumors

Melting point ca.

88-90 ºC

Boiling point ca.

354.07 °C

Density g/cm3 (20°C)

1.31g/cm3

Refractive index

1.57

Flash point

133.2°C

Stability

Stable under recommended storage conditions

Percent Composition

 C 46.25%, H 6.90%, Cl 15.17%, N 17.98%, O 13.69%

Packaging

required by customer

Delivery Time

overnight (USA/Canada); 3-5 days (worldwide)

Storage

Store at 4° C

Transport information

 by air/sea

 

Description

Lomustine is an alkylating nitrosourea compound that possesses antitumor activity similar to Carmustine (sc-204671) causing

DNA interstrand cross-linking. The compound is also a documented inhibitor of glutathione reductase, DLD(lipoamide dehydrogenase) and trypanothione reductase. Lomustine is a highly lipid soluble compound thus enabling it to cross the blood

brain barrier and rapidly disperse in tissue. In A2870 cells, Lomustine has been shown to induce p53 expression.

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