MGF (Mechano Growth Factor) MGF Mechano Growth Factor
Sequence:
H-Tyr-Gln-Pro-Pro-Ser-Thr-Asn-Lys-Asn-Thr-Lys-Ser-Gln-Arg-Arg-Lys-Gly-Ser-Thr-Phe-Glu-Glu-His-Lys-NH2
FM: C121H200N42O39
MW: 2867.14
Storage: Store at -20C. Keep container tightly closed. Store in a cool dry place.
Appearance: Lyophilzed white powder
Mechano Growth Factor (MGF) with sequence YQPPSTNKNTKSQRRKGSTFEEHK-NH2, is a novel splice variant of the insulin growth factor -1 (IGF-1), also known as IGF-1Ec in humans and IGF-1Eb in rodents. Studies have suggested that MGF plays a number of physiological roles because the failure in its expression may result to age-related loss of skeletal function. One included in its functions is its ability to become a potent neuroprotective as supported by the study that has shown functional copies of the MGF cDNA to be expressed in a plasmid vector which then protected facial neurons after nerve damage. One such failure is called sarcopenia. The appearance of MGF also initiates the upregulation of new protein synthesis.
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