IGF-1 LR3 Insulin-Like Growth Factor-I LR3 Insulin-Like Growth Factor-I LR3
Sequence:
H-Met-Phe-Pro-Ala-Met-Pro-Leu-Ser-Ser-Leu-Phe-Val-Asn-Gly-Pro-Arg-Thr-Leu-Cys-Gly-Ala-Glu-Leu-Val-Asp-Ala-Leu-Gln-Phe-Val-Cys-Gly-Asp-Arg-Gly-Phe-Tyr-Phe-Asn-Lys-Pro-Thr-Gly-Tyr-Gly-Ser-Ser-Ser-Arg-Arg-Ala-Pro-Gln-Thr-Gly-Ile-Val-Asp-Glu-Cys-Cys-Phe-Arg-Ser-Cys-Asp-Leu-Arg-Arg-Leu-Glu-Met-Tyr-Cys-Ala-Pro-Leu-Lys-Pro-Ala-Lys-Ser-Ala-OH.
MW: 9.1K
Storage: Store at -20C. Keep container tightly closed. Store in a cool dry place.
Appearance: Lyophilzed white powder
IGF-1 LR3, also known as Long R3 Insulin-like Growth Factor-I with 83 amino acids, is a human recombinant, single, non-glycosylated analog of IGF-I with the substitution of an Arginine (Arg) for the Glutamic Acid (Glu) at position 3, as well as a 13 amino acid extension peptide. This sequence change causes IGF-1 to avoid binding to proteins and allow it to have a much longer half life, around 20-30 hours. Due to this, it has been suggested that IGF-1 LR3 is more potent than the IGF-1 in many aspects such as increasing amino acid transport to cells, increasing glucose transport, increasing protein synthesis, decreasing protein degradation and so on.
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