Loratadine 79794-75-5 Loratadine
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Product Name: | Loratadine |
Synonyms: | LORATADINE;LORATADINE-D5;LORATIDINE;CLARATYNE;CLARITIN;ethyl 4-(8-chloro-5,6-dihydro-11h-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylate;4(8-CHLORO-5,6-DIHYDRO-11H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-YLIDENE)-1-PIPERIDINECARBOXYLATE;4-(8-CHLORO-5,6-DIHYDRO-11H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-YLIDENE)-1-PIPERIDINECARBOXYLIC ACID ETHYL ESTER |
CAS: | 79794-75-5 |
MF: | C22H23ClN2O2 |
MW: | 382.88 |
EINECS: | |
Product Categories: | Active Pharmaceutical Ingredients;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Histamine receptor;Amines;Heterocycles;Pharmaceutical intermediate;Other APIs |
Mol File: | 79794-75-5.mol |
Loratadine Chemical Properties |
mp | 134-136°C |
storage temp. | 2-8°C |
solubility | DMSO: 26 mg/mL, soluble |
form | powder |
color | white |
Stability: | Stable, but may be heat sensitive - refrigerate. Incompatible with strong oxidizing agents. |
Loratadine Usage And Synthesis |
Chemical Properties | White Crystalline Solid |
Usage | antinflammatory, analgesic, antipyretic |
Usage | Anti-histamine |
Usage | A nonsedating-type histamine H1-receptor |
Biological Activity | Peripheral histamine H 1 receptor antagonist (K i = 35 nM); devoid of central effects. Orally active antiallergic agent. |
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