lower price IPI145...

lower  price IPI145(duvelisib)( 1201438-56-3) supply

lower price IPI145(duvelisib)( 1201438-56-3) supply

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1 Gram

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  • Min.Order :1 Gram
  • Purity: 99%min
  • Payment Terms : L/C,D/A,D/P,T/T,Other

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1201438-56-3 duvelisib IPI-145

Quick Details

  • Appearance:white powder
  • Application:used for research
  • PackAge:aluminum foil bag
  • ProductionCapacity:1|Metric Ton|Day
  • Storage:Store in cool, dry, ventilated place
  • Transportation:by sea or by air

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Details:

  • Biological Activity

    Description Duvelisib (IPI-145, INK1197) is a novel and selective PI3K δ/γ inhibitor with Ki and IC50 of 23 pM/243 pM and 1 nM/50 nM, highly selective for PI3K δ/γ than other protein kinases. Phase 3.

    Chemical Information

     
    Molecular Weight (MW) 416.86
    Formula

    C22H17ClN6O

    CAS No. 1201438-56-3
    Storage 3 years -20℃powder
    6 months-80℃in solvent
    Synonyms Duvelisib, IPI-145, INK1197
     
    Solubility (25°C)* In vitro DMSO 83 mg/mL (199.1 mM)
    Water <1 mg/mL (<1 mM)
    Ethanol <1 mg/mL (<1 mM)
    In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
    <1 mg/ml means slightly soluble or insoluble.
     
    Chemical Name 1(2H)-Isoquinolinone, 8-chloro-2-phenyl-3-[(1S)-1-(9H-purin-6-ylamino)ethyl]-

 

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