Amisulpride 71675-8...

Amisulpride	71675-85-9

Amisulpride 71675-85-9

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1 Kilogram

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  • Min.Order :1 Kilogram
  • Purity: 98%
  • Payment Terms : L/C,D/A,D/P,T/T,

Keywords

71675-85-9 71675-85-9 C17H27N3O4S

Quick Details

  • Appearance:White or off-white Solid
  • Application:
  • PackAge:According to the demand of customer
  • ProductionCapacity:20|Metric Ton|Month
  • Storage:Sealed, dry, microtherm , avoid light and smell.
  • Transportation:According to the demand of customer

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Amisulpride Basic information
Product Name: Amisulpride
Synonyms: 4-AMINO-N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-5-(ETHYLSULFONYL)-2-METHOXYBENZAMIDE;AMISULPRIDE;AMINOSULTOPRIDE;DAN-2163;DENIBAN;SOCIAN;SOLIAN;4-amino-n-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-methoxybenzam
CAS: 71675-85-9
MF: C17H27N3O4S
MW: 369.48
EINECS: 275-831-7
Product Categories: Active Pharmaceutical Ingredients;Antipsychotic;Drug Analogues;Intermediates & Fine Chemicals;Pharmaceuticals;Dopamine receptor;DENIBAN
Mol File: 71675-85-9.mol
Amisulpride Structure
 
Amisulpride Chemical Properties
mp  124-128
storage temp.  2-8°C
solubility  DMSO: ≥5 mg/mL
form  solid
color  white
CAS DataBase Reference 71675-85-9(CAS DataBase Reference)
 
Safety Information
Hazard Codes  Xn
Risk Statements  22
Safety Statements  22-24/25
WGK Germany  3
RTECS  CV2308701
MSDS Information
Provider Language
Amisulpride English
SigmaAldrich English
 
Amisulpride Usage And Synthesis
Chemical Properties Off-White Solid
Usage Neuroleptic agent, an analogue of sulpiride. Used as an antipsychotic. Dopamine receptor antagonist
Usage Amisulpride is a neuroleptic agent, an analogue of Sulpiride (S689145). Amisulpride is used as an antipsychotic. Amisulpride is a dopamine receptor antagonist.
Biological Activity Potent, selective dopamine D 2 and D 3 receptor antagonist. K i values are 2.8 and 3.2 nM respectively for human D 2 and D 3 and > 1000 nM for human D 1 , D 4 and D 5 receptors. Shows selectivity for presynaptic dopamine autoreceptors at low doses and blocks postsynaptic D 2 /D 3 receptors at higher doses. Preferentially interacts with limbic D 2 -like receptors in vivo . Atypical antipsychotic/antischizophrenic agent with limited extrapyrimidal side effects and a profile distinct from that of haloperidol and remoxipride.

 

Details:

Amisulpride Basic information
Product Name: Amisulpride
Synonyms: 4-AMINO-N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-5-(ETHYLSULFONYL)-2-METHOXYBENZAMIDE;AMISULPRIDE;AMINOSULTOPRIDE;DAN-2163;DENIBAN;SOCIAN;SOLIAN;4-amino-n-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-methoxybenzam
CAS: 71675-85-9
MF: C17H27N3O4S
MW: 369.48
EINECS: 275-831-7
Product Categories: Active Pharmaceutical Ingredients;Antipsychotic;Drug Analogues;Intermediates & Fine Chemicals;Pharmaceuticals;Dopamine receptor;DENIBAN
Mol File: 71675-85-9.mol
Amisulpride Structure
 
Amisulpride Chemical Properties
mp  124-128
storage temp.  2-8°C
solubility  DMSO: ≥5 mg/mL
form  solid
color  white
CAS DataBase Reference 71675-85-9(CAS DataBase Reference)
 
Safety Information
Hazard Codes  Xn
Risk Statements  22
Safety Statements  22-24/25
WGK Germany  3
RTECS  CV2308701
MSDS Information
Provider Language
Amisulpride English
SigmaAldrich English
 
Amisulpride Usage And Synthesis
Chemical Properties Off-White Solid
Usage Neuroleptic agent, an analogue of sulpiride. Used as an antipsychotic. Dopamine receptor antagonist
Usage Amisulpride is a neuroleptic agent, an analogue of Sulpiride (S689145). Amisulpride is used as an antipsychotic. Amisulpride is a dopamine receptor antagonist.
Biological Activity Potent, selective dopamine D 2 and D 3 receptor antagonist. K i values are 2.8 and 3.2 nM respectively for human D 2 and D 3 and > 1000 nM for human D 1 , D 4 and D 5 receptors. Shows selectivity for presynaptic dopamine autoreceptors at low doses and blocks postsynaptic D 2 /D 3 receptors at higher doses. Preferentially interacts with limbic D 2 -like receptors in vivo . Atypical antipsychotic/antischizophrenic agent with limited extrapyrimidal side effects and a profile distinct from that of haloperidol and remoxipride.

 

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