High purity Deserpi...

High purity Deserpidine with best quality
High purity Deserpidine with best quality

High purity Deserpidine with best quality

Min.Order / FOB Price:Get Latest Price

10 Gram

Negotiable

  • Min.Order :10 Gram
  • Purity: ≥99%
  • Payment Terms : L/C,Other

Keywords

Deserpidine purity 99% Deserpidine high quality cas 131-01-1

Quick Details

  • Appearance:White crystalline powder
  • Application:Antihypertensive
  • PackAge:25kg/paper drum or as customers' requirements
  • ProductionCapacity:200|Kilogram|Month
  • Storage:sealed and stored in light-tight, shady and cool place
  • Transportation:by sea/by express

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Details:

Basic information

Deserpidine is an ester alkaloid drug isolated from Rauwolfia canescens (family Apocynaceae) with antipsychotic and antihypertensive properties that has been used for the control of high blood pressure and for the relief of psychotic behavior.

Product Name:

Deserpidine

Synonyms:

methyl 17-methoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylate;DESERPIDINE;Canescine;Harmonyl;Raunormine;Recanescine;Reserpidine;(1S,2R,3R,4aS,13bR,14aS)-2-methoxy-3-(3,4,5-trimethoxybenzoyl)oxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroisoquinolino[3,2-a]$b-carboline-1-carboxylic acid methyl ester

CAS:

131-01-1

MF:

C32H38N2O8

MW:

578.65272

Mol File:

131-01-1.mol

Deserpidine Structure

 

Pharmacology

Indication

For the treatment of hypertension.

Pharmacodynamics

Deserpidine, an alkaloid of Rauwolfia canescens, is used as an antihypertensive. Rauwolfia alkaloids work by controlling nerve impulses along certain nerve pathways. As a result, they act on the heart and blood vessels to lower blood pressure.

Mechanism of action

Deserpidine's mechanism of action is through inhibition of the ATP/Mg2+ pump responsible for the sequestering of neurotransmitters into storage vesicles located in the presynaptic neuron. The neurotransmitters that are not sequestered in the storage vesicle are readily metabolized by monoamine oxidase (MAO) causing a reduction in catecholamines.

 

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