2-(1H-Indol-3-yl)ethanamine

Min.Order / FOB Price:Get Latest Price

100 Gram	FOB Price: USD 1.0000

100 Gram

FOB Price: USD 1.0000

Min.Order :100 Gram
Purity: 98%
Payment Terms : L/C,T/T,Other

Keywords

2-(1H-Indol-3-yl)ethanamine 61-54-1 98%

Quick Details

Appearance:White to Orange Crystalline Powder
Application:Research
PackAge:According to customer's requirement
ProductionCapacity:1|Metric Ton|Day
Storage:2-8°C
Transportation:By air or courier

Superiority:

Shanghai Run-Biotech Co., Lted is a leading domestic pharmaceutical, biopharmaceutical, and health care products R & D outsourcing services company. As an innovation-driven and customer-focused company, Run Biotech provides a broad and integrated portfolio of services throughout the drug R&D process. Our services are designed to help our worldwide customers shorten the discovery and development time and lower the cost of drug and medical device R&D through cost-effective and efficient outsourcing solutions.

Based on our technical expertise and excellent research facilities, we successfully establish facilities, advanced R & D services technology platform. We will achieve leapfrog all-round development in the field of chemical synthesis, medicinal chemistry, biological and so on.

Run Biotech has further enhanced the integrated services with analytical services, bio-analytical services, process research, process development services, API manufacturing services, discovery biology, pharmacology, formulation services, biologics manufacturing services, antibody, biological research reagent manufacturing and sales services.

In Taiwan , Mainland China and Southeast Asia, Run Biotech has its own logistics center, provides the professional, personalized one-stop services, offers a variety of technologies and products and services for the world's major technology and industrial customers.

Details:

Tryptamine Basic information

Description Applications Plants Containing Tryptamine Pharmacology

Product Name:	Tryptamine
Synonyms:	(Amino-2 ethyl)-3 indole;(amino-2ethyl)-3indole;3-(2-aminoethyl)-indol;3-Indoleethylamine;beta-(3-Indolyl)ethylamine;Indol-3-ethylamine;Indole, 3-(2-aminoethyl)-;Tryptamin
CAS:	61-54-1
MF:	C10H12N2
MW:	160.22
EINECS:	200-510-5
Product Categories:	Inhibitors;Drug Intermediates;Indole;Indoles;Tryptamines;Amines;Heterocycles;Non-Chiral heterocyclic compounds
Mol File:	61-54-1.mol

Tryptamine Chemical Properties

Melting point	113-116 °C(lit.)
Boiling point	137 °C0.15 mm Hg(lit.)
density	0.9787 (rough estimate)
refractive index	1.6210 (estimate)
Fp	185 °C
storage temp.	2-8°C
solubility	water: soluble1g/L at 20°C
pka	10.2(at 25℃)
form	crystalline
color	white
PH	11.07 (10g/l, H2O, 24.7℃)
Water Solubility	negligible
Sensitive	Air Sensitive
Merck	14,9796
BRN	125513
CAS DataBase Reference	61-54-1(CAS DataBase Reference)
NIST Chemistry Reference	1H-Indole-3-ethanamine(61-54-1)
EPA Substance Registry System	1H-Indole-3-ethanamine(61-54-1)

Safety Information

Hazard Codes	Xi
Risk Statements	20/21/22-36/37/38-41-37/38-22
Safety Statements	24/25-36/37/39-36-26
WGK Germany	3
RTECS	NL4020000
F	8-23
HazardClass	IRRITANT
HS Code	28259080
HS Code	29339990

Tryptamine Usage And Synthesis

Description	Tryptamine is a monoamine alkaloid that can be synthesized by decarboxylation of the amino acid tryptophan. Notably, tryptamine can be found in fungi, plants, Amphibia, animals, and microbes. Tryptamine has an indole ring structure and a fused double ring that is composed of a benzene ring and a pyrrole ring, linked to an amino group by 2-carbon side chain. The indole ring is the vital nucleus of many complex natural products that have significance in drug discovery as well as some synthetic and non-synthetic drugs that are based on tryptamine skeleton. The chemical’s distinct structure is an approximation to the neurotransmitter serotonin as well-known drugs and hallucinogens. Tryptamine’s significance as psychedelic drugs, neuromodulator, and neurotransmitter is well understood due to its presence in mammalian brain in small amounts.
Applications	Analogs of tryptamine that are typically produced by its synthetic modification play a significant role in individuals due to the introduction of functionalities that are biologically active in its nucleus that may cause changes in the mental and physical status of the human brain. Substitutions on the indole ring at nitrogen and C-2 of its side chain produce numerous neuroactive compounds ranging from anti-migraine drugs to toxic substances, such as rizatriptan, sumatriptan, and zolmitriptan. A small amount of tryptamine is required due to its fatalities and intoxication for several reasons.
Plants Containing Tryptamine	In plants, tryptamine in small amounts acts as a promising phase to the plant hormone indole-3-acetic acid in one biosynthetic pathway. N, N-dimethyltryptamine (DMT) is a tryptamine derivative that is an active constituent for the hallucinogenic effect of brew known as the “vine of the souls.” Indigenous Amazonian tribes have traditionally used the drink for therapeutic purposes for effective treatment of some physical maladies and abuse disorders. Magic mushrooms are the most common fungi that contain tryptamine derivatives.
Pharmacology	Serotonin (5-hydroxytryptamine, 5-HT), which is a natural derivative of tryptamine is a significant signaling hormone that helps in the modulation and regulation of numerous processes within the central nervous system, for instance, cognition, sleep, temperature regulation, memory, and behavior. The mammalian brain contains small traces of tryptamine, which generally act as a modulator or neurotransmitter by releasing serotonin agents. It is also an enhancer of serotonergic activity. Only one minute is required for tryptamine to produce psychotropic phenomena when used recreationally. It has been associated with fatalities and intoxications for multiple reasons including low toxic concentrations.
Chemical Properties	White to Orange Crystalline Powder
Uses	Occurs in plants.
Uses	psychotropic
Definition	ChEBI: An aminoalkylindole consisting of indole having a 2-aminoethyl group at the 3-position.
Purification Methods	Crystallise tryptamine from *benzene, Et2O (m 114o) or pet ether (m 118o). It has UV: 222n 276, 282 and 291nm (EtOH) and max 226, 275, 281 and 290nm (HCl). [Beilstein 22 II 346, 22 III/IV 4319, 22/10 V 45.]