High purity Azithromycin with best quality

Product Name:

Azithromycin

Synonyms:

N-METHYL-11-AZA-10-DEOXO-10-DIHYDROERYTHROMYCIN A;11-(4-dimethylamino-3-hydroxy-6-methyl-oxan-2-yl)oxy-2-ethyl-3,4,10-tr;11-(4-DIMETHYLAMINO-3-HYDROXY-6-METHYL-TETRAHYDRO-PYRAN-2-YLOXY)-2-ETHYL-3,4,10-TRIHYDROXY-14-(5-HYDROXY-4-METHOXY-4,6-DIMETHYL-TETRAHYDRO-PYRAN-2-YLOXY)-3,5,6,8,10,12,13-HEPTAMETHYL-1-OXA-6-AZA-CYCLOPENTADECAN-15-ONE;9-DEOXO-9ALPHA-METHYL-9ALPHA-AZA-HOMOERYTHROMYCIN A;9-deoxo-9a-methyl-9a-aza-homoerythromycin a;AZITHROMYCIN;AZITHROMYCINE;1-oxa-6-azacyclopentadecan-15-one,13-((2,6-dideoxy-3-c-methyl-3-o-methyl-alpha

CAS:

83905-01-5

MF:

C38H72N2O12

MW:

748.993

Product Categories:

Antibiotics;Antibiotic;Antibiotic Explorer;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Antibiotics A to;Antibiotics A-FAntibiotics;AntiviralAntibiotics;Interferes with Protein SynthesisAntibiotics;MacrolidesEPA;veterinary medicine;Peptide Synthesis/Antibiotics;Pharmaceutical intermediate

Mol File:

83905-01-5.mol

Assay(potency)

≥ 945u/mg 

Water

≤5.0%

PH Value

9.0 ~ 11.0 

Specific rotation

-45~-49

Heavy metals 

≤25ppm 

Related substances 

≤2.0% 

Usage And Synthesis

Chemical Properties

White Crystalline Powder

Usage

Labelled Azithromycin, a semi-synthetic macrolide antibiotic; related to Erythromycin A. Antibacterial.

Azithromycin is a semi-synthetic, ring-expanded erythromycin, produced by a Beckmann rearrangement of erythromycin oxime and reduction to the imine ether, followed by reductive methylation. Azithromycin was the first of the azalides and was designed to improve stability and biological half-life of erythromycin A, as well as improve activity against Gram negative bacteria. Since its discovery in 1980 by Djokic and co-workers, azithromycin has enjoyed considerable therapeutic success.

Cephalosporin antibiotic

Azithromycin is a semi-synthetic, ring-expanded erythromycin produced by a Beckmann rearrangement of erythromycin oxime and reduction to the imine ether, followed by reductive methylation. Azithromycin was the first of the azalides and was designed to improve the stability and biological half-life of erythromycin A, as well as improve activity against Gram negative bacteria. Since its discovery in 1980 by Djokic and co-workers, azithromycin has enjoyed considerable therapeutic success.

Biological Activity

Macrolide antibiotic. Inhibits 50S ribosomal subunit formation and elongation at transpeptidation step in gram-positive and gram-negative organisms. Orally active with improved pharmacokinetics over erythromycin in mouse models.