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Details:
Description An odorless,white to off-white crystalline powder
Identification 1.Exhibit maxima at 267nm,277nm and 288nm
2.The retention times of the peaks for the cis-and trans-stereo isomers in the Chromatogram of the assay preparation corresponds to those of the Standard preparation as obtained in the Assay respectively.
3.The infrared absorption spectrum is concordant with the spectrum of sirolimus reference standard.
Assay 99%min
Heavy metals ≤20ppm
Water ≤0.5%
Ratio of isomer Trans-stereo isomer ≥95.0%
Impurity ≤2.0%