High purity Gefitin...

High purity Gefitinib with good quality
High purity Gefitinib with good quality

High purity Gefitinib with good quality

Min.Order / FOB Price:Get Latest Price

10 Gram

Negotiable

  • Min.Order :10 Gram
  • Purity: ≥99%
  • Payment Terms : L/C,T/T,Other

Keywords

Iressa purity 99% Gefitinib high quality cas 184475-35-2

Quick Details

  • Appearance:white powder
  • Application:Anti-tumour APIs
  • PackAge:25kg/paper drum or as customers' requirements
  • ProductionCapacity:200|Kilogram|Week
  • Storage:Guard against damp, Keep away from the sun.
  • Transportation:by sea/by express

Superiority:

1, High quality with competitive price:

  We are manufacturer and can provide high quality products with factory price.

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3, We have clients throughout the world.

  1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet your desire.

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Details:

Basic information

Product Name:

Gefitinib

Synonyms:

IRESSA;GEFITINIB;AKOS 91371;n-(3-chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine;N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine;ZD 1839;4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-;Gefitinib(TINIBS)

CAS:

184475-35-2

MF:

C22H24ClFN4O3

MW:

446.9

Product Categories:

Active Pharmaceutical Ingredients;Gefitinib;Molecular Targeted Antineoplastic;Intermediates & Fine Chemicals;Pharmaceuticals;Pharmaceutical intermediate;APIs;IRESSA;Anti-cancer&immunity;API;Inhibitors

Mol File:

184475-35-2.mol

Gefitinib Structure

 

Chemical Properties

melting point 

119-1200C

boiling ponit 

586.8 °C at 760 mmHg

density 

1.322 g/cm3

flashing point 

308.7 °C

vapor pressure 

9.48E-14 mmHg at 25°C

storage temp. 

Store at RT

 

Usage And Synthesis

Chemical Properties

Light-Yellow Crystalline Powder

Usage

Gefitinib (Iressa, ZD-1839) is an EGFR inhibitor for Tyr1173, Tyr992, Tyr1173 and Tyr992 in the NR6wtEGFR and NR6W cells with IC50 of 37 nM, 37nM, 26 nM and 57 nM, respectively.

Gefitinib is an antineoplastic.

Biological Activity

Orally active, selective inhibitor of EGFR tyrosine kinase (IC 50 = 23-79 nM). Shows minimal activity against ErbB2, KDR, c-flt, PKC, MEK and ERK-2. Blocks EGFR autophosphorylation and inhibits tumor growth in mice bearing a range of human xenografts.

 

About us:

Hubei Jusheng Technology Co., Ltd., is a large group corporation which engaged in the R&D and manufacture of chemicals, Pharmaceuticals and intermediates. We have earned ourselves a good reputation at home and abroad with advanced technology, standardized management and well established service systerm. We have developed to a very famous group corporation Enterprise in chemical industry step by step. 

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