High purity Sorafen...

High purity Sorafenib for Cancer treatment
High purity Sorafenib for Cancer treatment

High purity Sorafenib for Cancer treatment

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10 Gram

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  • Min.Order :10 Gram
  • Purity: ≥98%
  • Payment Terms : L/C,T/T,Other

Keywords

Sorafenib tosylate purity 98% Sorafenib high quality cas 284461-73-0

Quick Details

  • Appearance:pale yellow powder
  • Application:API
  • PackAge:25kg/paper drum or as customers' requirements
  • ProductionCapacity:200|Kilogram|Week
  • Storage:stored at dry, cool and avoid light
  • Transportation:by sea/by express

Superiority:

1, High quality with competitive price:

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Details:

Basic information

Product Name:

Sorafenib tosylate

Synonyms:

sorafenib;SORAFENIB-D3;SORAFENIB TOLSYLATE;RAF1 KINASE INHIBITOR II;N-(4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL)-((4-(2-(N-METHYL-CARBAMOYL)(4-PYRIDYLOXY))PHENYL)AMINO)CARBOXAMIDE;4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-n-methyl-pyridine-2-carboxamide;BAY 43-9006;SORAFENIB MESYLATE

CAS:

284461-73-0

MF:

C21H16ClF3N4O3

MW:

464.83

Product Categories:

Sorafinib;Molecular Targeted Antineoplastic;All Inhibitors;anti-neoplastic;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Pharmaceutical intermediate;Amines;Inhibitor;Bay 43-9006

Mol File:

284461-73-0.mol

Sorafenib tosylate Structure

 

Chemical Properties

melting point 

202-204°C

boiling point 

523.3 °C at 760 mmHg

density 

1.454 g/cm3

flashing point 

270.3 °C

storage temp. 

-20°C Freezer

 

Usage And Synthesis

Chemical Properties

Light Yellow Solid

Usage

A potent RAF kinase inhibitor. Antineoplastic

Multiple kinase inhibitor targeting both RAF kinase and receptor tyrosine kinases that promote angiogensis. Antineoplastic.

Sorafenib Tosylate (Bay 43-9006, Nexavar) is a small molecular inhibitor of VEGFR, PDGFR, c-Raf and B-Raf with IC50s of 18 nM, 10 nM, 3 nM and 15 nM, respectively.

Sorafenib Tosylate (Bay 43-9006) is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively.

 

About us:

Hubei Jusheng Technology Co., Ltd., is a large group corporation which engaged in the R&D and manufacture of chemicals, Pharmaceuticals and intermediates. We have earned ourselves a good reputation at home and abroad with advanced technology, standardized management and well established service systerm. We have developed to a very famous group corporation Enterprise in chemical industry step by step. 

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